Cardiac xenotransplantation is believed to have approached clinical application. However, this approach to advanced heart failure is burdened with a multitude of ethical issues. These issues need to be addressed openly and be broadly discussed in public. Only through an honest and transparent approach, it will be possible to engage the lay audience in the evaluation of pig to human transplant.
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Economics of reducing response time to foreign-animal disease in the United States with point-of-care diagnostic tests.
Prev Vet Med
September 2024
Centre of Excellence for Sustainable Food Systems, University of Liverpool, Liverpool UK. Electronic address:
Background: As low probability events, United States producers, value chain actors, and veterinary services (VS) have limited experience with identifying foreign animal disease (FAD), which can allow FADs to spread undetected. Point-of-care (POC) diagnostic testing may help reduce the time from detecting an initial suspect case to implementing actionable interventions compared to the current approach of only using laboratory diagnostic testing for disease diagnosis and confirmation. To evaluate the value of the reduced response time, we compare the associated costs between the two diagnostic approaches while accounting for the uncertainty surrounding the size of a FAD event.
View Article and Find Full Text PDFSedline Miscalculation of Depth of Anaesthesia Variables in Two Pigs Due to Electrocardiographic Signal Contamination.
Animals (Basel)
August 2023
Section of Anaesthesiology and Pain Therapy, Department of Clinical Veterinary Medicine, Vetsuisse Faculty, University of Bern, 3012 Bern, Switzerland.
Article Synopsis
- Two young pigs were anesthetized with propofol in an experimental study, and their anesthesia depth was monitored using clinical evaluations and the Sedline EEG-based monitor.
- In one pig (Case 1), abnormal data from the Sedline indicated increased brain activity during high doses of propofol, which was disputed by visual EEG observations.
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Are we smart enough to remember how smart animals are?
J Exp Psychol Gen
August 2023
School of Psychology, University of Kent.
Some theoretical perspectives suggest people overestimate animals' mental capacities (anthropomorphism), while others suggest the reverse (mind-denial). However, studies have generally not employed objective criteria against which the accuracy or appropriateness of people's judgments about animals can be tested. We employed memory paradigms, in which judgments are clearly right or wrong, in nine experiments (eight preregistered; = 3,162).
View Article and Find Full Text PDFChallenges and opportunities of smallholder pig production systems in Rwanda.
Trop Anim Health Prod
September 2022
Department of Agricultural Production (DAP), School of Agricultural Sciences (SAS), College of Agricultural & Environmental Sciences (CAES), Makerere University, Kampala, Uganda.
To decipher the dynamics, challenges, and opportunities of smallholder pig farming in Rwanda, a household survey was conducted in ten districts of the country. A total of 900 households selected randomly across four provinces and one city, 12 districts, 28 sectors, and villages were interviewed using a pretested printed questionnaire. Most of the respondents were heads of household: 70.
View Article and Find Full Text PDFLearning-based autonomous vascular guidewire navigation without human demonstration in the venous system of a porcine liver.
Int J Comput Assist Radiol Surg
November 2022
Institute for Anthropomatics and Robotics, Karlsruhe Institute of Technology, Engler-Bunte-Ring 8, 76131, Karlsruhe, Germany.
Purpose: The navigation of endovascular guidewires is a dexterous task where physicians and patients can benefit from automation. Machine learning-based controllers are promising to help master this task. However, human-generated training data are scarce and resource-intensive to generate.
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