AI Article Synopsis
- A new coumestan compound named 7,5'-dihydroxy-4'-(3''-hydroxy-3''-methyl--isobut-1''-enyl) was identified alongside five known compounds from the EtOAc-soluble extract of certain plant stems.
- The structures of these compounds were determined using various spectroscopic techniques.
- The new compound showed noteworthy cytotoxic effects on HeLa cancer cells, with an IC value of 6.5 μM, indicating its potential as a cancer treatment.
Article Abstract
A new coumestan named 7,5'-dihydroxy-4'-(3''-hydroxy-3''-methyl--isobut-1''-enyl) coumestan (), together with five known compounds (), was isolated from the EtOAc-soluble extract of the stems of . Their structures were elucidated based on extensive spectroscopic analyses. All the isolates were evaluated for cytotoxic activities against four human cancer cells including HepG2, A549, HeLa and MCF-7. Among them, the new compound was found to exhibit significant cytotoxic activity on HeLa cells with IC value of 6.5 μM.
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| http://dx.doi.org/10.1080/10286020.2021.1951713 | DOI Listing |
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