AI Article Synopsis

  • The study examines the prevalence and risk factors for double vision (diplopia) in patients with Parkinson Disease (PD), revealing that 18.1% of PD patients experience diplopia compared to 6.3% of controls.
  • Factors such as older age, non-white race, longer disease duration, and increased severity of motor and non-motor symptoms are linked to higher rates of diplopia in PD patients.
  • These findings highlight that diplopia is a significant concern for those with PD and is related to overall disease severity.

Article Abstract

Background: Some patients with Parkinson Disease (PD) report double vision, but its prevalence and determinants are unknown.

Objectives: To determine the prevalence and risk factors for diplopia in PD.

Methods: Using data from 26,790 PD patients and 9257 controls in the Fox Insight Study, we compared the prevalence of diplopia using the Non-Movement Symptom Questionnaire. Associations with age, race, gender, disease duration, and scores on MDS-UPDRS part II, and Penn Parkinson's Daily Activity Questionnaire were assessed with generalized estimating equations.

Results: The point prevalence of diplopia was higher in PD (18.1%) than controls (6.3%,  < 0.001) at baseline, and 28.2% of all PD patients reported diplopia at least once during the study (period prevalence). PD patients with diplopia were more likely to be older, non-white, have greater disease duration, and report greater motor, non-motor, and daily activity limitations.

Conclusions: Diplopia is common and associates with motor and non-motor severity in PD.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8287164PMC
http://dx.doi.org/10.1002/mdc3.13220DOI Listing

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