The objective of this study was to investigate the effects of (i) the difference in the beam qualities on the presampled modulation transfer function (MTF) using the edge method and (ii) the readout direction of the edge profile for the photostimulable phosphor (PSP) system. The International Electrotechnical Commission (IEC) defined a technique using the "radiation qualities based on a phantom made up of an aluminum added filter" (RQA). A general radiographic system with a tube voltage of 50 kV and 9.7 mm of additional aluminum filtration was used to conform the x-ray to the IEC-specified beam quality definition RQA3. Additionally, we employed two different beams with tube voltages of 60 and 70 kV using a dental x-ray unit. The MTF was measured in the readout direction from low-to-high exposure regions and vice versa with respect to the scanning and subscanning directions of the PSP system. The difference in the 50%MTF value for all directions between 60 and 70 kV averaged less than . The 50%MTF of RQA3 was on average 0.2 lower than the value for 60 kV for each direction. For all beam qualities, no difference was observed between the MTFs measured in the readout direction from the low-to-high exposure regions and vice versa. The MTFs, measured using the dental x-ray unit, were unaffected by the tube voltage, and they were slightly higher than those measured using the RQA3. Furthermore, the MTF was unaffected by the differences in the readout directions of the edge profile.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291077 | PMC |
http://dx.doi.org/10.1117/1.JMI.8.4.043501 | DOI Listing |
Biosens Bioelectron
December 2024
Shenzhen Bay Laboratory, Shenzhen, 518132, China. Electronic address:
Here, we developed nanobody-assisted nanoluciferase fragment complementation for in situ measurement and visualization of endogenous protein-protein interaction (NanaPPI). When an interaction occurs, primary antibodies for two proteins bring the proximity of secondary nanobody-fused small/large fragment to reassemble into an intact NanoLuc variant, thus transforming interaction events to luminescent signals in situ with high sensitivity. Compared to proximity ligation assay, NanaPPI has a similar signal-to-background ratio, but it is more convenient with faster procedures, easier readout and lower cost.
View Article and Find Full Text PDFElife
January 2025
Institut für Biologie, Humboldt Universität zu Berlin, Berlin, Germany.
Since the pioneering work by Moeller, Szabo, and Bullock, weakly electric fish have served as a valuable model for investigating spatial and social cognitive abilities in a vertebrate taxon usually less accessible than mammals or other terrestrial vertebrates. These fish, through their electric organ, generate low-intensity electric fields to navigate and interact with conspecifics, even in complete darkness. The brown ghost knifefish is appealing as a study subject due to a rich electric 'vocabulary', made by individually variable and sex-specific electric signals.
View Article and Find Full Text PDFSci Rep
December 2024
School of Electrical and Electronic Engineering, Nanyang Technological University, 639798, Singapore, Singapore.
The outstanding performance of superconducting nanowire single-photon detectors (SNSPDs) has expanded their application areas from quantum technologies to astronomy, space communication, imaging, and LiDAR. As a result, there has been a surge in demand for these devices, that commercial products cannot readily meet. Consequently, more research and development efforts are being directed towards establishing in-house SNSPD manufacturing, leveraging existing nano-fabrication capabilities that can be customized and fine-tuned for specific needs.
View Article and Find Full Text PDFBiosensors (Basel)
November 2024
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China.
Point-of-care (POC) immunoassays have become convincing alternatives to traditional immunosensing methods for the sensitive and real-time detection of targets. Immunoassays based on gas-generating reactions were recently developed and have been used in various fields due to their advantages, such as rapid measurement, direct reading, simple operation, and low cost. Enzymes or nanoparticles modified with antibodies can effectively catalyze gas-generating reactions and convert immunorecognition events into gas pressure signals, which can be easily recorded by multifunctional portable devices.
View Article and Find Full Text PDFJ Thorac Oncol
December 2024
Moores Cancer Center, University of California San Diego, La Jolla, CA 92037, USA; Department of Medicine, University of California San Diego, La Jolla, CA 92037, USA; Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Introduction: Copy-number (CN) loss of chromosome 9p, or parts thereof, impair immune response and confer ICT resistance by direct elimination of immune-regulatory genes on this arm, notably IFNγ genes at 9p24.1, and type-I interferon (IFN-I) genes at 9p21.3.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!