Two new stilbene derivatives, named strebluses C and D, were isolated from the EtOAc-soluble fraction of the stems of (Moraceae). Its absolute configuration was elucidated based on NMR spectroscopic data interpretation and optical rotation calculation. Streblus C possesses strong tyrosinase inhibitory activity with an IC value of 0.01 M. Docking studies of and with -tyrosinase were carried out to analyze their interactions. The analysis of the docked poses confirmed that showed better binding affinity for -tyrosinase than that of .
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266447 | PMC |
http://dx.doi.org/10.1155/2021/5561176 | DOI Listing |
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