COVID-19 causes a pandemic situation that increased the paid or unpaid responsibilities (home and job) on women and brought significant changes in their lifestyle, resulting in psychological and emotional stress. This paper draws attention to the triple burden on the women during this time when certain roles are supposed to be performed by the women regardless she is employed or homemaker. The paper highlights the challenges faced by women educationists in making themselves comfortable with the work-life balance with emerging challenges such as new technology-based innovative teaching methods and various learning software's, apps, platforms, etc.. The paper employs in-depth interviews of teachers belonging to three categories i.e. primary, secondary, and higher education. The findings reported that female teachers agreed that pandemic had affected their daily life schedule. This leaves a deep effect on their mental and psychological health due to multiple attentions they pay towards home management, child & elders extra care, challenges due to work from home pattern of organizations, increased attention to students due to online teaching, etc. The paper presents the implications for the society and government to understand the women's pressure so that a happy and satisfied life is there for all with no gender discrimination.
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http://dx.doi.org/10.1007/s10639-021-10645-6 | DOI Listing |
Gerontologist
January 2025
Center on the Ecology of Early Development (CEED), Boston College, Boston, Massachusetts, USA.
Background And Objectives: Chronic kidney disease (CKD) is a major public health concern that uniquely impacts older Black Americans, a population also likely to have family members also diagnosed with CKD. This study aimed to (1) describe how participants viewed their decision preferences considering the experiences of family, and friends previously diagnosed with CKD, and (2) to understand how these social complexities informed their own decisions for future CKD care.
Research Design And Methods: Utilizing a phenomenologically-informed approach, this study explored participants' perceptions of how patients and their family members' experiences with CKD influenced treatment-related decision-making.
BMC Cancer
January 2025
Department of Breast Surgery, the First Hospital of China Medical University, Shenyang, Liaoning, 110001, China.
Background: Not all breast cancer (BC) patients can benefit from neoadjuvant therapy (NAT). A poor response may result in patients missing the best opportunity for treatment, ultimately leading to a poor prognosis. Thus, to identify an effective predictor that can assess and predict patient response at early time points, we focused on circulating tumor DNA (ctDNA), which is a vital noninvasive liquid biopsy biomarker.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Department of General Surgery, Tangdu Hospital, Air Force Medical University, Xi'an, 710038, P. R. China.
Leaky and structurally abnormal blood vessels and increased pressure in the tumor interstitium reduce the infiltration of CAR-T cells in solid tumors, including triple-negative breast cancer (TNBC). Furthermore, high burden of tumor cells may cause reduction of infiltrating CAR-T cells and their functional exhaustion. In this study, various effector-to-target (E:T) ratio experiments are established to model the treatment using CAR-T cells in leukemia (high E:T ratio) and solid tumor (low E:T ratio).
View Article and Find Full Text PDFAm J Respir Crit Care Med
January 2025
University of Utah, Division of Cardiovascular Medicine, Department of Medicine, Salt Lake City, Utah, United States.
Rationale: Guidelines recommend patients with pulmonary arterial hypertension (PAH) be referred to pulmonary hypertension (PH) centers, but little is known about where care is actually delivered in the United States (US).
Objectives: To use prescription patterns to estimate the proportion of PAH care delivered at US PH centers and explore factors associated with location of care.
Methods: This retrospective study analyzed claims from the Komodo database in adults who received ≥1 PAH prescription between March 2021 and February 2022.
BMJ Open Respir Res
January 2025
Department of Respiratory Sciences, University of Leicester, Leicester, UK.
Background: Tuberculosis (TB) diagnosis in the UK is impacted by delay and suboptimal culture-based microbiological confirmation rates due to the high prevalence of paucibacillary disease. We examine the real-world clinical utility of Xpert MTB/RIF Ultra (Xpert-Ultra) as a diagnostic test and biomarker of transmissible infection in a UK TB service.
Methods: Clinical specimens from suspected TB cases triple tested (smear microscopy, mycobacterial culture and Xpert-Ultra) at University Hospitals of Leicester NHS Trust (1 March 2018-28 February 2019) were retrospectively analysed.
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