AI Article Synopsis
- Mediastinal masses are often found in children and can be difficult to diagnose because of limited sampling options.
- This article helps pathologists by outlining the key hematologic diagnoses for pediatric mediastinal masses and suggesting additional tests to ensure accurate identification.
- It discusses common types of lymphomas, such as Hodgkin lymphoma and T-lymphoblastic leukemia/lymphoma, while also touching on rarer cases and non-cancerous conditions like benign cysts and infections.
Article Abstract
Mediastinal masses commonly present in children and may pose diagnostic challenges, particularly with limited sampling. This article aids the pathologist by reviewing the hematologic differential diagnosis of a pediatric mediastinal mass, along with ancillary testing useful for rendering the correct diagnosis. A review of the more common lymphomas is presented, including classic Hodgkin lymphoma, T-lymphoblastic leukemia/lymphoma, and primary mediastinal (thymic) large B-cell lymphoma, along with brief mentions of less common entities such as gray zone lymphoma and thymoma as well as non-neoplastic conditions such as benign cysts and infections.
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| http://dx.doi.org/10.1016/j.cll.2021.03.011 | DOI Listing |
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