AI Article Synopsis
- Zinc finger proteins are a large and diverse family of proteins primarily known for their role as DNA binding transcription factors, but they can also interact with RNA, proteins, lipids, and poly-ADP-ribose.
- Recent studies suggest that these proteins play a significant role in regulating the immune system both before and after transcription, although their exact mechanisms remain unclear.
- This review focuses on the various types of zinc finger proteins involved in immune regulation and discusses their specific regulatory mechanisms.
Article Abstract
Background: Zinc finger proteins encompass one of the unique and large families of proteins with diversified biological functions in the human body. These proteins are primarily considered to be DNA binding transcription factors; however, owing to the diverse array of zinc-finger domains, they are able to interact with molecules other than DNA like RNA, proteins, lipids and PAR (poly-ADP-ribose). Evidences from recent scientific studies have provided an insight into the potential functions of zinc finger proteins in immune system regulation both at the transcriptional and post transcriptional level. However, the mechanism and importance of zinc finger proteins in the regulation of immune response is not very well defined and understood. This review highlights in detail the importance of zinc finger proteins in the regulation of immune system at transcriptional and post transcriptional level.
Conclusion: Different types of zinc finger proteins are involved in immune system regulation and their mechanism of regulation is discussed herewith.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8310398 | PMC |
| http://dx.doi.org/10.1007/s11033-021-06556-x | DOI Listing |
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