The pursuit of sustainability in the field of road asphalt pavements calls for effective decision-making strategies, referring to both the technical and environmental sustainability of the solutions. This study aims to compare the life cycle impacts of several pavement solution alternatives involving, in the binder and base layers, some eco-designed, hot- and cold-produced asphalt mixtures made up of recycled aggregates in substitution for natural filler and commercial recycled polymer pellets for dry mixture modification. The first step focused on the technical and environmental compatibility assessment of the construction and demolition waste (CDW), jet grouting waste (JGW), fly ash (FA), and reclaimed asphalt pavement (RAP). Then, three non-traditional mixtures were designed for the binder layer and three for the base layer and characterized in terms of the stiffness modulus. Asphalt pavement design allowed for the definition of the functional units of Life Cycle Assessment (LCA), which was applied to all of the pavement configurations under analysis in a "from cradle to grave" approach. The LCA results showed that the best performance was reached for the solutions involving a cold, in-place recycled mixture made up of RAP and JGW in the base layer, which lowered all the impact category indicators by 31% on average compared to those of the traditional pavement solution. Further considerations highlighted that the combination of a cold base layer with a hot asphalt mixture made up of CDW or FA in the binder layer also maximized the service life of the pavement solution, providing the best synergistic effect.
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http://dx.doi.org/10.3390/ma14143867 | DOI Listing |
Menopause
January 2025
National Institute of Health, Cheongju, Republic of Korea.
Objectives: We examined the health-related quality of life (HRQoL) during menopause transition (MT) among middle-aged Korean women.
Methods: This cross-sectional study comprised 2,290 middle-aged women who completed web-based questionnaires between 2020 and 2022. Based on self-reported menstrual cycle patterns, menopause status was classified as premenopausal, early or late transition, or postmenopausal.
J Nurs Res
February 2025
Nursing Department, Nursing and Occupational Therapy College, and Health and Care Research Group (GISyC), Universidad de Extremadura, Cáceres, Spain.
Background: Menstruation is a physiological process that may be accompanied by pain, headache, edema, emotional changes, and other symptoms, all of which affect quality of life. Although the results of some studies indicate lifestyle habits can affect the menstrual cycle and associated symptoms, few have investigated this issue, and even fewer have explored the impact of these symptoms on quality of life, in Spanish women.
Purpose: The objectives of this study were to determine the prevalence of dysmenorrhea and premenstrual syndrome (PMS) among students at a Spanish university, assess the impact of these conditions on quality of life, and analyze the relationship among lifestyle habits, dysmenorrhea, and PMS.
PLoS One
January 2025
Department of Pharmacology & Toxicology, The University of Texas Medical Branch, Galveston, Texas, United States of America.
Severe acute respiratory syndrome coronavirus-1 (SARS-CoV-1) and -2 (SARS-CoV-2) are beta-coronaviruses (β-CoVs) that have caused significant morbidity and mortality worldwide. Therefore, a better understanding of host responses to β-CoVs would provide insights into the pathogenesis of these viruses to identify potential targets for medical countermeasures. In this study, our objective is to use a systems biology approach to explore the magnitude and scope of innate immune responses triggered by SARS-CoV-1 and -2 infection over time in pathologically relevant human lung epithelial cells (Calu-3/2B4 cells).
View Article and Find Full Text PDFEnviron Technol
February 2025
Technology Institute, University of Passo Fundo, Passo Fundo, RS, Brazil.
Food waste offers a potential source for bioethanol production, but productivity depends on the chemical composition of the raw materials and the processes involved. However, assessment of the environmental sustainability of these processes is often absent and can be carried out using the Life Cycle Assessment (LCA) methodology. This study aimed to perform an LCA on bioethanol production from mixtures of different wastes, including tubers, fruits, and processed foods, focusing on the gate-to-gate phase.
View Article and Find Full Text PDFAnnu Rev Entomol
January 2025
Department of Biology and Molecular Sciences Research Center, University of Puerto Rico, San Juan, Puerto Rico.
Novel traits in the order Lepidoptera include prolegs in the abdomen of larvae, scales, and eyespot and band color patterns in the wings of adults. We review recent work that investigates the developmental origin and diversification of these four traits from a gene-regulatory network (GRN) perspective. While prolegs and eyespots appear to derive from distinct ancestral GRNs co-opted to novel body regions, scales derive from in situ modifications of a sensory bristle GRN.
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