Introduction: The extent of exposure to occupational carcinogens is not well characterized in Iran, and little is known about the burden of occupational cancer.
Objectives: This study aimed to describe exposure to occupational carcinogens and occupational epidemiology studies in Iran.
Methods: Relevant studies up to January 2021 in Iran were identified through three databases (PubMed, Web of Science, and Google Scholar).
Results: Forty-nine publications from 2009 to 2020 (one cohort, 11 case-control, 34 exposure monitoring studies, and three cancer burden studies) were included. The exposure monitoring studies were conducted mainly in the petroleum industry, metal industry, manufacturing of electronics, manufacturing of plastics, construction industry, and service industry. A few of the case-control studies also reported increased risk of cancers in relation to work in those industries.
Conclusions: Occupational cancer epidemiology in Iran is at an early stage. Both epidemiological and exposure monitoring studies are generally limited in size to provide robust evidence of occupational cancer risks. A coherent strategy to estimate the occupational cancer burden in Iran should start with conducting epidemiological studies along with systematic monitoring of occupational carcinogens for use in hazard control and research.
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http://dx.doi.org/10.3390/cancers13143581 | DOI Listing |
Int J Environ Res Public Health
December 2024
Institute of Integrated Atmospheric Environment, 1-2-8 Koraku, Bunkyo, Tokyo 112-0004, Japan.
Concerns regarding the health risks associated with employe exposure to volatile chemicals during gasoline refueling necessitates rigorous investigation and effective countermeasures. This study aims to evaluate the efficacy of vapor recovery systems in mitigating exposure risks during gasoline refueling. Employee exposure to volatile organic compounds, aldehydes, carbon monoxide, and fine particulate matter (PM) was assessed at gasoline stations with and without vapor recovery systems.
View Article and Find Full Text PDFEpidemiology
January 2025
Epidemiology Branch, Division of Intramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.
Background: We evaluated air emissions of industrial compounds, many of which have carcinogenic or endocrine disrupting properties, in relation to breast cancer incidence.
Methods: Using the United States Environmental Protection Agency's Toxics Release Inventory, we quantified air emissions of 28 compounds near Sister Study participants' residences during the 10 years leading up to study enrollment (2003-2006; n=46,150). We used Cox proportional hazards regression to estimate adjusted hazard ratios (HR) and 95% confidence intervals (CI) for associations of residential emission levels of single pollutants with incident breast cancer.
Toxins (Basel)
January 2025
Graduate Toxicology Program, Department of Veterinary Sciences, Utah State University, Logan, UT 84322, USA.
It has been known since the early days of the discovery of aflatoxin B1 (AFB1) that there were large species differences in susceptibility to AFB1. It was also evident early on that AFB1 itself was not toxic but required bioactivation to a reactive form. Over the past 60 years there have been thousands of studies to delineate the role of ~10 specific biotransformation pathways of AFB1, both phase I (oxidation, reduction) and phase II (hydrolysis, conjugation, secondary oxidations, and reductions of phase I metabolites).
View Article and Find Full Text PDFAnn Work Expo Health
January 2025
Institute for Risk Assessment Sciences, Utrecht University, Yalelaan 2, 3584 CM Utrecht, the Netherlands.
Objectives: Trichloroethylene (TCE) is a carcinogen that has been causally linked to kidney cancer and possibly other cancer sites including the liver and lymphatic system. Its use in China has increased since the early 1990s due to the growing metal and electronic industries. We aimed to summarize the major sources of occupational exposure to TCE over time in China.
View Article and Find Full Text PDFBMC Public Health
January 2025
Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, CA, USA.
This short review addresses the pressing issue of lung cancer among firefighters, a population facing unique occupational hazards such as smoke inhalation and asbestos exposure. With lung cancer being a leading global cause of death, the study emphasizes the disproportionate burden on firefighters. Notably, wildfire smoke, containing carcinogenic elements, poses a rising significant threat to firefighters' respiratory health.
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