Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cell.2021.06.015 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A quality assurance protocol for reliable and reproducible multi-TI arterial spin labeling perfusion imaging in rat livers.
MAGMA
January 2025
Medical Physics Group, Institute of Diagnostic and Interventional Radiology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Objective: To establish an arterial spin labeling (ASL) protocol for rat livers that improves data reliability and reproducibility for perfusion quantification.
Methods: This study used respiratory-gated, single-slice, FAIR-based ASL imaging with multiple inversion times (TI) in rat livers. Quality assurance measures included: (1) introduction of mechanical ventilation to ensure consistent respiratory cycles by controlling the respiratory rate (45 bpm), tidal volume (10 ml/kg), and inspiration: expiration ratio (I:E ratio, 1:2), (2) optimization of the trigger window for consistent trigger points, and (3) use of fit residual map and coefficient of variance as metrics to assess data quality.
Sustainable improvement of granite sludge dust properties using microbially induced carbonate precipitation (MICP): strength enhancement, erosion prevention, and dust mitigation.
Environ Sci Pollut Res Int
January 2025
Department of Civil Engineering, National Institute of Technology Warangal, Warangal, 506004, India.
Granite sludge dust (GSD), a significant byproduct of granite processing globally, poses severe environmental and public health challenges, with India alone generating 200 million tons annually. The conventional use of GSD in soil stabilization and construction materials is limited to 20-30%, underscoring the urgent need for sustainable repurposing solutions within the circular economy catering to broader bulk utilization. Unlike traditional techniques, repurposing granite dust using microbially induced calcite precipitation (MICP) offers a sustainable low-impact and eco-friendly ground improvement solution.
View Article and Find Full Text PDFHexafluoropropylene Oxide Trimer Acid Is an Unsafe Substitute to Perfluorooctanoic Acid Due to Its Remarkable Liver Accumulation in Mice Disclosed by Comprehensive Toxicokinetic Models.
Environ Sci Technol
January 2025
Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, P. R. China.
Hexafluoropropylene oxide trimer acid (HFPO-TA, CF(CFOCF(CF))COOH) is widely used as an alternative to perfluorooctanoic acid (PFOA), but whether it is a safe alternative requires further evaluation. In this study, male mice were exposed to three dosages (0.56, 2.
View Article and Find Full Text PDFAssociations between structural brain changes and blood neurofilament light chain protein in treatment-resistant schizophrenia.
Aust N Z J Psychiatry
January 2025
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Parkville, VIC, Australia.
Objective: Around 30% of people with schizophrenia are refractory to antipsychotic treatment (treatment-resistant schizophrenia). Abnormal structural neuroimaging findings, in particular volume and thickness reductions, are often described in schizophrenia. Novel biomarkers of active brain pathology such as neurofilament light chain protein are now expected to improve current understanding of psychiatric disorders, including schizophrenia.
View Article and Find Full Text PDFLetter to the editor: Comparing the coagulation and platelet parameters of women with premature ovarian insufficiency with those of age-matched controls: A case-control study.
Int J Gynaecol Obstet
January 2025
Retired Professor in Hematology, Faculty of Medicine, Ufuk University, Ankara, Turkey.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!