We propose an intrinsic three-dimensional Fabry-Pérot type interferometer, coined "higher-order interferometer," that is based on the chiral hinge states of second-order topological insulators and cannot be mapped to an equivalent two-dimensional setting because of higher-order topological obstructions. Quantum interference patterns in the two-terminal conductance of this interferometer are controllable not only by tuning the strength but also, particularly, by rotating the direction of the magnetic field applied perpendicularly to the transport direction. Remarkably, the conductance exhibits a characteristic beating pattern with multiple frequencies depending on the field strength and direction in a unique fashion. Our novel interferometer thus provides feasible and robust magnetotransport signatures for hinge states of higher-order topological insulators.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1103/PhysRevLett.127.026803 | DOI Listing |
HCA Healthc J Med
December 2024
Michigan State University College of Medicine, East Lansing, MI.
Introduction: While male breast carcinoma is a relatively uncommon occurrence, its incidence is on the rise, potentially attributed to sporadic pathophysiological mechanisms, primarily involving hormonal imbalances. Invasive apocrine carcinoma represents a small fraction of global breast malignancies, with limited instances reported among male patients in the literature. The clinical presentation of an apocrine breast carcinoma closely resembles that of other breast cancer subtypes, as it is most often described as a solitary ulcerative nodular lesion occupying a retro-areolar region of the breast.
View Article and Find Full Text PDFNatl Sci Rev
January 2025
College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China.
China's pursuit of carbon neutrality targets hinges on a profound shift towards low-carbon energy, primarily reliant on intermittent and variable, yet crucial, solar and wind power sources. In particular, low-solar-low-wind (LSLW) compound extremes present a critical yet largely ignored threat to the reliability of renewable electricity generation. While existing studies have largely evaluated the impacts of average climate-induced changes in renewable energy resources, comprehensive analyses of the compound extremes and, particularly, the underpinning dynamic mechanisms remain scarce.
View Article and Find Full Text PDFScience
January 2025
Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore.
Axions, hypothetical elementary particles that remain undetectable in nature, can arise as quasiparticles in three-dimensional crystals known as axion insulators. Previous implementations of axion insulators have largely been limited to two-dimensional systems, leaving their topological properties in three dimensions unexplored in experiment. Here, we realize an axion insulator in a three-dimensional photonic crystal and probe its topological properties.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
Southern University of Science and Technology, Department of Materials Science and Engineering, NO.1088,Xueyuan Avenue,Nanshan District, 518055, Shenzhen, CHINA.
Tin dioxide (SnO2) stands as a promising material for the electron transport layer (ETL) in perovskite solar cells (PSCs) attributed to its superlative optoelectronic properties. The attainment of superior power conversion efficiency hinges critically on the preparation of high-quality SnO2 thin films. However, conventional nanoparticle SnO2 colloids often suffer from inherent issues such as numerous oxygen vacancy defects and film non-uniformity.
View Article and Find Full Text PDFJ Med Chem
January 2025
Immunology Research Unit GlaxoSmithKline Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
Therapeutics promoting the endogenous production of IL-10 have the potential to restore homeostasis in inflammatory disorders such as inflammatory bowel disease (IBD). Here we describe the identification of a series of IL-10 upregulators based on a pyrimidyl-piperidine scaffold through a high throughput phenotypic CD4 T-cell multiplex assay. optimization of the initial hit yielded a lead with good potency and an clearance profile, compound 3-7, which additionally demonstrated efficacy in a murine endotoxin challenge PK-PD mechanistic model.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!