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http://dx.doi.org/10.1371/journal.ppat.1009710 | DOI Listing |
Fungal Genet Biol
December 2024
Department of Endodontics, The Affiliated Stomatological Hospital, Nanjing Medical University, Nanjing, China; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China. Electronic address:
Candida albicans (C. albicans), a common fungal pathogen, is responsible for infections such as oral candidiasis. Given the widespread misuse of antifungal medications and the increasing resistance, it is critical to explore new strategies to eradicate C.
View Article and Find Full Text PDFMicrob Pathog
December 2024
Universidade Regional do Cariri - URCA, Rua Cel. Antônio Luiz, 1161 - Pimenta, Crato- CE.
Candidiasis is an infectious disease caused by some fungi of the genus Candida. In Brazil, the incidence rate is higher than in European countries and the United States, and health problems occur mainly due to the virulence factors of the fungi, which have made treatment with commercial drugs difficult. Considering the context, plants rich in phenolic compounds, such as those of the genus Piper, have been studied due to their antimicrobial properties.
View Article and Find Full Text PDFBioorg Chem
December 2024
Department of Industrial and Environmental Microbiology, Faculty of Biology and Biotechnology, Institute of Biological Sciences, Maria Curie-Skłodowska University, Akademicka 19, 20-033 Lublin, Poland. Electronic address:
Biomimetic catalysis using porphyrins enables gentle oxidation of terpenes with molecular oxygen and light. This study explores the photooxidation of (-)-myrtenol under visible light to synthesize new terpenoid products with promising biological activity. Among the porphyrins tested, tetraphenylporphyrin (HTPP) exhibited the highest catalytic efficiency and stability in chloroform, producing myrtenal epoxide (ME) as the main product (with a molar conversion of myrtenol of 66.
View Article and Find Full Text PDFCell Mol Biol (Noisy-le-grand)
November 2024
Water Resources Engineering Department, College of Engineering, University of Duhok, Kurdistan Region- Iraq.
Candida albicans is an opportunistic fungal pathogen. It's a dimorphic fungus with hyphal form that can penetrate and proliferate the oral mucosa. Occlusal guard materials come into direct contact with the oral mucosa and saliva when worn for extended periods, the occlusal guard acts as a reservoir for C.
View Article and Find Full Text PDFMycopathologia
December 2024
Dermatology Hospital, Southern Medical University, Guangzhou, China.
We presented a case of chronic mucocutaneous candidiasis (CMC) due to STAT1 GOF mutation with recurrent enteritis and intestinal obstruction. A 33-year-old woman complained of recurrent oral erosion and finger (toe) nails damage for over 30 years. Candida albicans were cultured from the oral mucosa and nails.
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