Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.3109/03630268708998016 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Winding Road to Health Care Equity in Sickle Cell Disease.
Clin Lab Med
December 2024
Hematology Division, Department of Laboratory Medicine and Pathology, University of Washington; Harborview Medical Center, 3NJ345.1, Box 359743, 325 9th Avenue, Seattle, WA 98104, USA.
Sickle cell disease (SCD) is a genetic disorder where red blood cells sickle, causing anemia and pain. Historically linked to marginalized groups, SCD saw little progress in treatment strategies for decades. Addressing these requires holistic strategies including dedicated centers, education, patient inclusion, and tackling implicit bias.
View Article and Find Full Text PDFSocial Vulnerability and Sickle Cell Disease Mortality in the US.
JAMA Netw Open
September 2024
Division of Hematology, Department of Internal Medicine, McGovern Medical School at the University of Texas Health Science Center at Houston (UTHealth Houston).
Article Synopsis
- Social determinants of health (SDOH) significantly affect health outcomes, including mortality rates for sickle cell disease (SCD), even with improvements in treatments.
- This study analyzed SCD mortality data from 2016 to 2020, using county-level SDOH data to assess the relationship between social vulnerability and death rates across different population quartiles.
- Findings revealed that higher SVI scores correlate with significantly increased mortality, with a rate ratio of 4.90 for individuals in high vulnerability areas compared to low vulnerability, highlighting the impact of socioeconomic factors on health outcomes for SCD patients.
A large cohort of Hb H disease in northeast Thailand: A molecular revisited, diverse genetic interactions and identification of a novel mutation.
Clin Chim Acta
July 2024
Centre for Research and Development of Medical Diagnostic Laboratories, Faculty of Associated Medical Sciences, Khon Kaen University, Khon Kaen, Thailand. Electronic address:
Background And Aims: To update the molecular characteristics of α-thalassemia in northeast Thailand, the molecular basis and genetic interactions of Hb H disease were examined in a large cohort of patients.
Materials And Methods: A study was done on 1,170 subjects with Hb H disease and various genetic interactions encountered during 2009-2023. Hb and DNA analyses were carried out.
Mortality related to sickle cell disease and COVID-19 in Brazil, 2020.
Rev Assoc Med Bras (1992)
May 2024
Universidade de São Paulo (retired), Faculty of Public Health, Department of Epidemiology - São Paulo (SP), Brazil.
Objective: The ability to cause death is the definitive measure of an infectious disease severity, particularly one caused by a novel pathogen like severe acute respiratory syndrome-CoV-2 (COVID-19). This study describes sickle cell disease-related mortality issues during the COVID-19 pandemic in Brazil.
Methods: The provisional 2020 mortality data originated from the public databases of the Mortality Information System and were investigated using the multiple-cause-of-death methodology.
Prevalence of arboviruses in sickle cell disease patients from two different regions of Brazil, the North and Northeast.
Braz J Infect Dis
May 2024
Fundação Oswaldo Cruz (FIOCRUZ), Instituto Gonçalo Moniz, Salvador, BA, Brazil.
Sickle Cell Disease (SCD) is a hereditary disease characterized by extravascular and intravascular hemolysis and clinical variability, from mild pain to potentially life-threatening. Arboviruses include mainly Zika (ZIKV), Chikungunya (CHKV), and Dengue (DENV) virus, and are considered a public and social health problem. The present cross-sectional observational study aimed to investigate the prevalence of arbovirus infection in SCD patients from two Brazilian cities, Salvador and Manaus located in Bahia and Amazonas states respectively.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!