Executive functions (EFs) and intelligence (IQ) are phenotypically correlated. In twin studies, latent variables for EFs and IQ display moderate to high heritability estimates; however, they show variable genetic correlations in twin studies spanning childhood to middle age. We analyzed data from over 11,000 children (9- to 10-year-olds, including 749 twin pairs) in the Adolescent Brain Cognitive Development (ABCD) Study to examine the phenotypic and genetic relations between EFs and IQ in childhood. We identified two EF factors-Common EF and Updating-Specific-which were both related to IQ (rs = 0.64-0.81). Common EF and IQ were heritable (53%-67%), and their genetic correlation (rG = 0.86) was not significantly different than 1. These results suggest that EFs and IQ are phenotypically but not genetically separable in middle childhood, meaning that this phenotypic separability may be influenced by environmental factors.
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http://dx.doi.org/10.1111/desc.13150 | DOI Listing |
JAMA Neurol
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Takeda Development Center Americas, Inc, Cambridge, Massachusetts.
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Epilepsia
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Brain and Mind Electrophysiology Laboratory, Multimedia Systems Department, BioTechMed Center, Gdansk University of Technology, Gdansk, Poland.
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Department of Occupational Therapy, Faculty of Rehabilitation, Niigata University of Health and Welfare, Niigata, JPN.
Transcranial magnetic stimulation (TMS) is an effective intervention for improving cognitive impairment in patients with stroke. However, its effectiveness in the subdomains of cognition is conflicting and not clearly established. This systematic review assessed the efficacy of TMS in improving executive function, attention, and memory in this population.
View Article and Find Full Text PDFFront Psychiatry
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School of Psychology, Fujian Normal University, Fuzhou, China.
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UC San Diego Health Sciences, University of California San Diego, San Diego, CA, USA.
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