AI Article Synopsis

  • The study aimed to identify risk factors for death in individuals severely affected by COVID-19, using data from a cohort of adults in Acre, Brazil, between March and September 2020.
  • Analyzing over 57,700 individuals, the findings showed a significant incidence and mortality rate of COVID-19, with several key risk factors identified, including male gender, age over 60, dyspnea, and underlying health conditions like heart disease and diabetes.
  • The conclusion emphasizes that male sex, older age, and specific health issues greatly increase the risk of death from COVID-19 in affected individuals.

Article Abstract

Objective: To analyze risk factors for death in individuals with severe acute respiratory syndrome due to COVID-19.

Methods: This was a retrospective cohort study, comprised of adult individuals with COVID-19, from March to September 2020, notified by the Epidemiological Surveillance System in the state of Acre, Brazil. Cox regression was used.

Results: Among 57,700 individuals analyzed, the incidence was 2,765.4/100,000 inhabitants, and mortality was, 61.8/100,000 inhabitants. The risk factors for death were: being male (HR=1.48 -95% CI 1.25;1.76), age ≥60 years (HR=10.64 -95% CI 8.84;12.81), symptom of dyspnea (HR=4.20 -95% CI 3.44;5.12) and multimorbidity (HR=2.23 -95% CI 1.77;2.81), with emphasis on heart disease and diabetes mellitus. 'Sore throat' and 'headache' were symptoms present in mild cases of COVID-19.

Conclusion: Being male, elderly, having heart disease, diabetes mellitus and dyspnea were characteristics associated with death due to COVID-19.

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Source
http://dx.doi.org/10.1590/S1679-49742021000300018DOI Listing

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