A typical clinical symptom of human norovirus infection is projectile vomiting. Although norovirus RNA and viral particles have been detected in vomitus, infectivity has not yet been reported. We detected replication-competent norovirus in 25% of vomit samples with a 13-fold to 714-fold increase in genomic equivalents, confirming infectious norovirus.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8314841PMC
http://dx.doi.org/10.3201/eid2708.210011DOI Listing

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