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A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy. | LitMetric

A metal-organic cage-based nanoagent for enhanced photodynamic antitumor therapy.

Chem Commun (Camb)

College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Normal University, Jinan 250014, P. R. China.

Published: August 2021

Herein, we report, for the first time, a Pd6L8(NO3)5.4(ICG)6.6 (ICG = indocyanine green) cage-based hexagonal nanoplate (3) via a combined nanoprecipitation and solid-state anion-exchange approach. Nanoplate 3 possesses enhanced near-infrared (NIR) light-triggered 1O2 generation, high cellular uptake selective lysosome-targeting ability, and, consequently, excellent antineoplastic activity.

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Source
http://dx.doi.org/10.1039/d1cc02629aDOI Listing

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