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Commentary: Early-in-life Isoflurane Exposure Alters Resting-State Functional Connectivity in Juvenile Non-human Primates - a Role for Neuroinflammation?
J Immunol Sci
May 2024
Department of Anesthesiology, Columbia University Medical Center, New York, NY, USA.
The concern about anesthesia-induced developmental neurotoxicity (AIDN) in infants and young children arises from animal studies indicating potential long-term neurobehavioral impairments following early-in-life anesthesia exposure. While initial clinical studies provided ambiguous results, recent prospective assessments in children indicate associations between early-in-life anesthesia exposure and later behavioral alterations. Ethical constraints and confounding factors in clinical studies pose challenges in establishing a direct causal link and in investigating its mechanisms.
View Article and Find Full Text PDFLetter to the Editor: ICU- and ventilator-free days with isoflurane or propofol as a primary sedative - A post- hoc analysis of a randomized controlled trial.
J Crit Care
October 2023
ULB University, Centre Hospitalier Universitaire Brugmann, Brussels, Belgium.
Authors response: "ICU- and ventilator-free days with isoflurane or propofol as a primary sedative - A post-hoc analysis of a randomized controlled trial".
J Crit Care
October 2023
University Hospital Ulm, Department of Emergency Medicine, Ulm, Germany. Electronic address:
Is banning desflurane an essential measure to reduce global warming? Additional issues raised.
Eur J Anaesthesiol
July 2023
From the Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan (TT).
Anesthetic MAC: Origin, Utility, and Nomenclature Revisited.
Anesthesiology
June 2022
Department of Anesthesiology, Duke University School of Medicine, Durham, North Carolina.
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