AI Article Synopsis
- * A case study is presented involving a 19-year-old patient who experienced chest pain, leading to the discovery of a right mediastinal mass with pleural effusion and swollen lymph nodes, diagnosed as a yolk sac non-seminomatous germ cell tumor.
- * Following biopsy results showing elevated alpha-fetoprotein levels, the patient underwent 4 cycles of chemotherapy with etoposide, ifosfamide, and platinum salts, followed by complete surgical removal
Article Abstract
The mediastinal malignant germ cells tumor represents less than 0.5% of thoracic tumors, although the mediastinum is one of the main extragonadic locations of these tumors. In the majority of cases, young people are those most affected. The prognosis of mediastinal malignant germ cells tumors is poor, especially non-seminomatous germ tumors. In this article, we report a rare case of a young 19-years-old patient treated for a mediastinal germ cell tumor of yolk sac. The patient presented a chest pain; the chest computed tomography (CT) showed a right paramedian mediastinal mass with a pleural effusion associated with supraclavicular and cervical lymph nodes. Biopsy revealed a non-seminomatousgerm cell tumor of yolk sac. The exams showed elevated alpha-fetoprotein (AFP), without any meaningful elevation of other serictumor markers. The patient received 4 cycles of chemotherapy based on etoposide, ifosfamide and platinum salts then a complete excision of the mass.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8265249 | PMC |
| http://dx.doi.org/10.11604/pamj.2021.38.330.23730 | DOI Listing |
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