AI Article Synopsis

  • - The study explored how tobacco smoking affects the prevalence of melanocytic nevi (moles) and lentigines (age spots) among a group of smokers and matched nonsmokers.
  • - A total of 59 smokers and 60 nonsmokers were examined, but the results showed no significant differences in the number of nevi or lentigines between the two groups, regardless of sun exposure.
  • - The conclusion indicates that tobacco use does not appear to influence the prevalence of these skin conditions, suggesting that smoking may not be a risk factor in this context.

Article Abstract

Background: Melanocytic nevi have a complex evolution influenced by several endogenous and exogenous factors and are known risk factors for malignant melanoma. Interestingly, tobacco use seems to be inversely associated with melanoma risk. However, the association between tobacco use and nevi and lentigines has not yet been evaluated.

Methods: We investigated the prevalence of nevi, atypical nevi, and lentigines in relation to tobacco smoking in a cohort of 59 smokers and 60 age- and sex-matched nonsmokers, using a questionnaire and performing a total body skin examination by experts.

Results: No significant differences were detected between smokers and nonsmokers in the numbers of nevi, atypical nevi, and lentigines in sun-exposed areas (p = 0.966, 0.326, and 0.241, respectively) and in non-sun-exposed areas (p = 0.095, 0.351, and 0.546, respectively).

Conclusion: Our results revealed no significant differences in the prevalence of nevi, atypical nevi, and lentigines between smokers and nonsmokers in sun-exposed and non-sun-exposed areas.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291632PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0254772PLOS

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