AI Article Synopsis
- Fungal keratitis (FK) is a serious eye disease that can lead to vision loss, often triggered by factors like eye injuries, contact lens use, and improper use of medications.
- Current treatments include antifungal drugs and surgical options, but the underlying immune processes involved in FK are not fully understood.
- This review focuses on recent findings about the immune mechanisms in FK to help develop better treatments and protective strategies against the disease.
Article Abstract
Fungal keratitis (FK) is a refractory disease that poses a serious threat to vision, with common risk factors like eye trauma, contact lens wearing, topical corticosteroids and antibiotic abuse. Nowadays, topical and systemic anti-fungal drugs and ocular surgeries are still the main therapeutic modalities. However, the pathogenesis of FK, especially the immunologic mechanism within it, has not yet been deeply clarified. A better understanding of the pathogenesis of FK is imperative for more effective therapies and prognosis. Meanwhile, the immune protection strategies are also urgently required to manage FK. This review highlights recent advances in the immunologic mechanism in the pathogenesis of FK, in hope of providing valuable reference information for more effective anti-fungal treatment.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243179 | PMC |
| http://dx.doi.org/10.18240/ijo.2021.07.20 | DOI Listing |
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