Research was performed into the prevalence of concurrent parasite infection among 23 patients with onchocerciasis and 13 onchocerciasis-negative controls in Sierra Leone, West Africa. Stools, urine sediments and bloodsmears were examined for ova, parasites and microfilariae. Results showed the presence of Hookworm, Schistosoma mansoni, Trichuris trichiura and Ascaris lumbricoides. A positive relationship was found between O. volvulus and Hookworm infection. The effects of polyparasitism on immunodiagnosis and the need for further research is discussed.
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BMC Res Notes
January 2025
Helen Keller International, New York, USA.
Objective: Sierra Leone, a country where onchocerciasis is endemic in 14 of the 16 districts, was the focus of our investigation. Despite 17 rounds of annual ivermectin treatment since 2005, a report circulated by a local politician indicated an increase in cases of suspected onchocerciasis-related vision impairment in two villages (Mangobo and Petifu) in Tonkolili district. In response, the National Neglected Tropical Disease Program conducted a comprehensive investigation.
View Article and Find Full Text PDFTrop Med Infect Dis
November 2024
Department of Mathematics, University of Alioune Diop, Diourbel P.O. Box 30, Senegal.
Neglected tropical diseases (NTDs) with skin manifestations present a significant health and societal problems challenge worldwide. This study aimed to analyzed factors associated with the knowledge, attitudes and practices (KAPs) of primary healthcare workers (HCW) concerning NTDs with skin manifestations in the Dakar region of Senegal. We conducted a cross-sectional study utilizing a semi-structured questionnaire which was administered to eligible HCW (general practitioners, nurses and midwives) working at the 24 health centers located in the Dakar region.
View Article and Find Full Text PDFEpilepsia Open
November 2024
Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Onchocerciasis, commonly known as river blindness, is a neglected tropical disease caused by the parasite Onchocerca volvulus. It can lead to blindness and visual impairment. Studies have also demonstrated a link between onchocerciasis and epilepsy, with there being a correlation between onchocerciasis endemicity and epilepsy prevalence.
View Article and Find Full Text PDFPLoS Negl Trop Dis
November 2024
Center for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Introduction: Filarial pathogens are described to inhabit and affect subcutaneous and lymphatic tissues of the human host. To date, little is known on how much oral health might be affected by filarial infections, even though involvement of the oro-facial region is pathophysiologically possible. Therefore, we conducted this systematic review of the literature to help reduce the current evidence gap.
View Article and Find Full Text PDFPLoS Negl Trop Dis
September 2024
Infectious Diseases Division, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America.
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