Oncocytoma of the eyelid is a rare neoplasm. Oncocytoma associated with an ocular surface squamous neoplasm, namely conjunctival intraepithelial neoplasia, is very hard to find in the literature. Herein we report a case of a 53-year-old male who presented with a swelling in the right lower lid over the last 6 years, along with a growth in the conjunctiva of the same eye for the last 2 years and encroaching upon the cornea for the last 4 months. Excision biopsy of the lower lid mass showed histopathological features consistent with oncocytoma. The conjunctival tissue revealed conjunctival intraepithelial neoplasia 3 (severe dysplasia). This case documents a rare synchronous dual ocular neoplasia, a very unlikely coexistence of oncocytoma with conjunctival intraepithelial neoplasia.
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http://dx.doi.org/10.4322/acr.2020.235 | DOI Listing |
Vet Dermatol
January 2025
Department of Veterinary Medicine, University of Perugia, Perugia, Italy.
Background: In humans, the presence of an even distribution of melanocytes within the epidermal basal layer allows for uniform pigmentation in healthy and young individuals. Moreover, despite high variability in skin colours and tones, interindividual melanocyte density variability is low. However, dogs display a high intraindividual pigmentary variability in different anatomical areas.
View Article and Find Full Text PDFJ Fr Ophtalmol
December 2024
Cornea and Refractive Surgery Department, Asociación para Evitar la Ceguera en México, I.A.P., Mexico City, Mexico.
Purpose: To evaluate the clinical outcomes of topical 5-fluorouracil (5-FU) 1% as first-line therapy for giant ocular surface squamous neoplasia (OSSN).
Materials And Methods: This was a non-comparative cohort study. We included patients with biopsy-proven giant OSSN in a tertiary-care setting.
Ocul Surf
November 2024
Department of Ophthalmology, University of Cyprus Medical School, Nicosia, Cyprus. Electronic address:
Purpose: The purpose of this review is to explore the molecular foundations of ocular surface squamous neoplasia (OSSN), focusing on the genetic and epigenetic aspects. While current management strategies include surgical excision and medical therapies, the understanding of OSSN's molecular basis remains limited, hindering the development of targeted treatments.
Methods: A comprehensive MEDLINE search was conducted for literature published between January 1993 and October 2023.
Ophthalmic Plast Reconstr Surg
November 2024
Department of Ophthalmology and Visual Sciences, University of Adelaide, Adelaide, South Australia.
Purpose: Intraepithelial sebaceous gland carcinoma is a rare form of sebaceous gland carcinoma, with 10 published case reports to date. The authors report the clinical, histological, and prognostic features of this rare carcinoma.
Methods: This is a multicenter retrospective case series of patients from 3 Australian sites.
Jpn J Ophthalmol
November 2024
Department of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ward, Kyoto, 602-0841, Japan.
Purpose: To investigate the visual prognosis of ocular surface squamous neoplasia (OSSN) after tumor resection and ocular surface reconstruction, and clarify factors that influence recurrence.
Study Design: Retrospective cohort study.
Methods: Medical records of all patients who underwent surgical treatment for OSSN at our hospital between January 1996 and December 2019 were reviewed.
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