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Effects of iopromide contrast agents on kidney iNOS expression and tubular histopathology alterations.
Narra J
December 2024
Department of Urology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Contrast-induced acute kidney injury is a common complication marked by reduced kidney function within 48 hours of contrast administration. The aim of this study was to evaluate renal function, anatomy, and molecular changes at 24 hours, 48 hours, and 72 hours post-iodinated contrast media (ICM) administration. This true-experimental study used a post-test-only control group design.
View Article and Find Full Text PDFPrediction of post-contrast acute kidney injury by bedside ultrasonography.
BMC Emerg Med
January 2025
Department of Emergency Medicine, Recep Tayyip Erdoğan University Training and Research Hospital, Rize, 53020, Turkey.
Background: The incidence of contrast-induced acute kidney injury (CI-AKI) in the general population ranges from 0.6 to 2.3%, whereas for specific high-risk patients, the incidence can reach more than 30-40%.
View Article and Find Full Text PDFThe Impact of Insulin Resistance on the Development of Post-PCI Contrast-Induced Nephropathy in Non-Diabetic STEMI.
Acta Cardiol Sin
January 2025
Department of Cardiology, Faculty of Medicine, Inonu University, Malatya, Turkey.
Aims: Contrast-induced nephropathy (CIN) is a condition characterized by rapidly decreasing renal funciton following by the application of contrast material. Precutaneous coronary intervention (PCI) is a life-saving treatment method that should be applied under emergent conditions. Unfortunately, the incidence of CIN after PCI is common.
View Article and Find Full Text PDFCoronary artery disease and percutaneous coronary intervention in patients with severe chronic kidney disease.
Prog Cardiovasc Dis
January 2025
Department of Cardiology, St Francis Hospital and Heart Center, Roslyn, New York, USA; New York Institute of Technology, Old Westbury, New York, USA. Electronic address:
Coronary artery disease (CAD) is the leading cause of mortality among patients with chronic kidney disease (CKD), presenting unique challenges in diagnosis and management. Advanced CKD patients often present with atypical symptoms, and conventional diagnostic and interventional approaches carry risks, including contrast-induced nephropathy and the potential need for renal replacement therapy. These risks have led to the phenomenon of "renalism," where necessary procedures may be deferred due to concerns over renal injury.
View Article and Find Full Text PDFClinical Characteristics and Outcomes of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention: An Observational Cohort Study.
Glob Heart
January 2025
Adult Cardiology Department, Aswan Heart Centre, Magdi Yacoub Foundation, Aswan, Egypt.
Article Synopsis
- The study focused on elderly patients (70+) undergoing primary percutaneous coronary intervention (pPCI) for ST-elevation myocardial infarction (STEMI) at a tertiary center in Upper Egypt, highlighting a growing concern for cardiovascular disease in aging populations.
- The research included data from 3,627 patients, finding that 15.9% were elderly, with significantly higher in-hospital mortality rates, particularly among octogenarians (23.3%) compared to younger patients (4%).
- Elderly patients showed distinct clinical characteristics, such as higher rates of hypertension and chronic kidney disease, and were more likely to have severe complications post-procedure, emphasizing the need for tailored strategies in managing this demographic in cardiovascular care.
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