Infusion of latex beads into isolated perfused rat livers transiently increased glucose output, perfusate lactate/pyruvate ratio and portal vein pressure, mimicking hepatic effects of heat-aggregated IgG (HAG). Indomethacin attenuated hepatic responses to latex beads, and extracellular calcium was required for full expression of hepatic responses. Prior infusion of HAG inhibited the glycogenolytic response to latex beads, supporting a common mechanism of action for the two agents.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF01116505 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High-affinity uric acid clearance based on motile β-CD/F-127 polyrotaxane microspheres for enhanced diabetic wound repair.
Carbohydr Polym
March 2025
State Key Laboratory of Bioactive Molecules and Druggability Assessment, Institute of Biomedical Engineering, Jinan University, Guangzhou 510632, China. Electronic address:
Hyperuricemia-related diabetic wounds are notoriously difficult to treat due to elevated uric acid (UA) levels, excessive reactive oxygen species (ROS), and chronic inflammation. Current therapies often fail to address these underlying causes, underscoring the need for innovative approaches that not only clear UA but also mitigate inflammation and promote tissue regeneration. In this study, we developed a polyrotaxane-based microsphere (HPR MS) system conjugated with 4,5-diamino-2-thiouracil (DT) to achieve high-affinity UA clearance without increasing cytotoxicity.
View Article and Find Full Text PDFN-chlorination of urea-formaldehyde resin microspheres for antibacterial regenerated cellulose fibers.
Int J Biol Macromol
January 2025
Institute of Functional Textiles and Advanced Materials, College of Textiles & Clothing, Qingdao Key Laboratory of Flame-Retardant Textile Materials, State Key Laboratory of Bio-fibers and Eco-textiles, Qingdao University, Qingdao 266071, China. Electronic address:
Regenerated cellulose fibers are required for widespread antibacterial applications across various fields. N-halamines have been extensively studied and are regarded as a promising candidate for antibacterial purposes. In this work, we focus on investigating the chlorination performance of urea-formaldehyde resin microspheres (UFRs) and using them as antibacterial additives incorporated into the spinning dope to fabricate antibacterial viscose fibers.
View Article and Find Full Text PDFMarine algal polysaccharides for drug delivery applications: A review.
Int J Biol Macromol
January 2025
Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt. Electronic address:
In recent decades, there has been a growing interest in the use of polysaccharides that exhibit biological activity for a wide range of innovative applications. This is due to their nontoxicity, biodegradability, biocompatibility, and therapeutic properties. The diverse properties of polysaccharides derived from marine algae make them a promising strategy for the construction of drug delivery systems (DDSs).
View Article and Find Full Text PDFFacile Fabrication of Monodisperse Vinyl Hybrid Core-Shell Silica Microsphere with Short Range Radial Channel in bi-phase System.
Small
January 2025
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, College of Chemistry & Materials Science, Northwest University, Xi'an, 710127, China.
The development of monodisperse hybrid silica microspheres with highly regular pore structure and uniform distribution of functional groups have significant value in the biomolecular separation field. In this work, the short range ordered pore channels are precisely constructed onto the non-porous silica microsphere surface by a bi-phase assembly method, and the cylindrical silica channel introduced a plethora of vinyl groups by "one-pot" co-condensation to form vinyl hybrid silica shell. As hydrophilic interaction chromatography (HILIC) stationary phase, the vinyl hybrid core-shell silica microsphere is simply modified with zwitterion glutathione (SiO@SiO-GSH), in which the HILIC enrichment process is significantly shortened due to its specific porous characteristics.
View Article and Find Full Text PDFRepackable microfluidic molecularly imprinted solid-phase extraction coupled with mass spectrometry (μMISPE-MS) for rapid analysis of mycotoxin in agri-foods: an example of zearalenone.
Lab Chip
January 2025
Department of Food Science and Agricultural Chemistry, McGill University Macdonald Campus, Sainte-Anne-de-Bellevue, Quebec, H9X 3V9, Canada.
Mycotoxins are detectable in 60-80% of food crops, posing significant threats to human health and food security, and causing substantial economic losses. Most mitigation approaches focus on detecting mycotoxins with standard methods based on liquid chromatography coupled with mass spectrometry (LC-MS). Typical MS methods require extensive sample preparation and clean-up due to the matrix effect, followed by time-consuming LC separation, complicating the analysis process and limiting analytical throughput.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!