Leprosy is currently uncommon in Europe: the diagnosed cases are almost all imported from endemic areas. We report on an autochthonous case of borderline lepromatous leprosy in a 71-year-old Portuguese woman. The case was complicated by a reversal reaction and then by erythema nodosum leprosum. A literature review identified 18 reported cases of European autochthonous leprosy since 2000; all but one were observed in Mediterranean countries. Therefore, active clusters of leprosy persist in Europe, particularly in Spain, Greece, Portugal, and Italy.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ijid.2021.07.023 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Molecular and Serological Surveillance for and in Wild Red Squirrels () from Scotland and Northern England.
Animals (Basel)
July 2024
Department of Infectious Diseases, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Leprosy is a poverty-associated infectious disease in humans caused by or , often resulting in skin and peripheral nerve damage, which remains a significant public health concern in isolated areas of low- and middle-income countries. Previous studies reported leprosy in red squirrels in the British Isles, despite the fact that autochthonous human cases have been absent for centuries in this region. To investigate the extent of and presence in wild red squirrels in the northern UK, we analyzed 220 blood/body cavity fluid samples from opportunistically sampled red squirrels (2004-2023) for specific antibodies against phenolic glycolipid-I, a cell wall component specific for these leprosy bacilli.
View Article and Find Full Text PDFMore on Autochthonous Leprosy in the United States. Reply.
N Engl J Med
September 2023
Los Angeles General Medical Center, Los Angeles, CA
More on Autochthonous Leprosy in the United States.
N Engl J Med
September 2023
Universidad Nacional de San Juan, San Juan, Argentina
A modelling analysis of a new multi-stage pathway for classifying achievement of public health milestones for leprosy.
Philos Trans R Soc Lond B Biol Sci
October 2023
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK.
Several countries have come close to eliminating leprosy, but leprosy cases continue to be detected at low levels. Due to the long, highly variable delay from infection to detection, the relationship between observed cases and transmission is uncertain. The World Health Organization's new technical guidance provides a path for countries to reach elimination.
View Article and Find Full Text PDFAutochthonous Leprosy in the United States.
N Engl J Med
June 2023
Los Angeles General Medical Center, Los Angeles, CA
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!