Objective: A large number of people experience misophonia. In 2013, the Amsterdam Study Group recommended diagnostic criteria for misophonia. However, misophonia is not yet included in the Diagnostic and Statistical Manual of Mental Disorders. This report is the first report on drug use that directly affects misophonia and demonstrates a 14-year-old adolescent girl with misophonia successfully treated with fluoxetine.
Methods: The patient's misophonia symptoms had been continuing for approximately 2 years, and her quality of life was significantly reduced. Psychotherapy conditions could not be applied, and fluoxetine 10 mg/d was started and increased to 20 mg/d after a week. At the second-month follow-up, because of partial improvement, fluoxetine dose was increased to 30 mg/d.
Results: At the fourth-month follow-up, there was a 40% decrease in Amsterdam Misophonia Scale score with a 70% decrease in the children's global assessment scale scores. By the 16th week, the overall functionality level was good at the end.
Conclusions: Fluoxetine may be used as an effective drug in the treatment of misophonia.
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Article Synopsis
- Misophonia is a sound sensitivity disorder often starting in childhood, and there are currently no effective questionnaires to assess its severity in youth.
- This study introduced and validated two new questionnaires: the Misophonia Screening List-Child and Youth for screening, and the Amsterdam Misophonia Scale-Youth (AMISOS-Y) for measuring severity.
- The questionnaires were tested on a diverse sample and showed strong psychometric properties (α = 0.95-0.96), but future studies are needed for broader validation in community and clinical settings.
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