AI Article Synopsis

  • The study examines the prevalence and clinical features of pneumococcal coinfection in COVID-19 patients, finding a 2% occurrence among 18 patients.
  • Most patients (88%) showed radiological changes upon admission, with 29% having elevated procalcitonin levels, and the mortality rate was recorded at 12%.
  • The authors suggest starting antimicrobial treatment if there's a moderate to high suspicion of bacterial coinfection, but emphasize the importance of discontinuing antibiotics if not confirmed.

Article Abstract

Objective: Currently the prevalence of pneumococcal coinfection in patients with COVID-19 is unknown. In this work we present its clinical characteristics, evolution and treatment.

Methods: Retrospective data collection from August to October 2020 in two hospitals in the Murcia region.

Results: Eighteen patients had COVID-19 diagnosed by PCR and pneumococcal infection confirmed by antigenuria, which represented a prevalence of 2%. A total of 88% had radiological alterations upon admission (two patients had an X-ray within normality) and 29% had elevated procalcitonin. Mortality in our series was 12%.

Conclusions: It could be reasonable to consider the start of antimicrobial therapy in those cases in which there is a moderate or high suspicion of bacterial coinfection, being essential the early suspension of antibiotic treatment if it is not confirmed.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8638830PMC
http://dx.doi.org/10.37201/req/151.2020DOI Listing

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