Severe COVID-19 arises from the convergence of inadequate pre-existing immunity and a host response that damages, rather than repairs, tissues. We outline clinical presentations of COVID-19 that are likely driven by dysregulated host immunity, discuss potential mechanisms underlying pathological responses, and highlight important areas for basic research on this topic.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8279571 | PMC |
| http://dx.doi.org/10.1016/j.chom.2021.06.018 | DOI Listing |
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