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Haemodynamic profiling: when AI tells us what we already know.
Br J Anaesth
February 2025
Anesthesiology, Critical Care and Pain Medicine Division, Department of Medicine and Surgery, University of Parma, Parma, Italy.
Machine learning (ML) algorithms hold significant potential for extracting valuable clinical information from big data, surpassing the processing capabilities of the human brain. However, it would be naïve to believe that ML algorithms can consistently transform data into actionable insights. Clinical studies suggest that in some instances, they tell clinicians what they already know or can plainly see.
View Article and Find Full Text PDFMeasuring parents' awareness, identification, and communication practices about acquaintance abuse against children in Pakistan.
Arch Pediatr
January 2025
Department of Mass Communication, Allama Iqbal Open University, Islamabad, Pakistan.
Background: Child Sexual Abuse (CSA) is a growing healthcare issue worldwide. However, the acquittance rape is one of the underrepresented phenomena due to certain social and cultural concerns. Consequently, the role of parents is of greater significance to ensure the safety of their children outside and insider of their homes.
View Article and Find Full Text PDFAn ethnographic study to develop a taxonomy of lies for communicating with people with moderate to severe dementia.
Nurs Ethics
February 2025
CNTW NHS Foundation Trust.
Background: There is no definition of what constitutes a lie when working with people with moderate to severe dementia. Lies are often defined as therapeutic with no evidence of how therapeutic value is gauged. There is no previous research that observes lies being told or the impact the lies have on people with dementia.
View Article and Find Full Text PDFDual-roles and beyond: values, ethics, and practices in forensic mental health decision-making.
Med Health Care Philos
January 2025
Centre for Ethics, Law and Mental Health, University of Gothenburg, Gothenburg, Sweden.
Forensic mental health services (FMHS) involve restricting certain individual rights to uphold or promote other ethical values - the restriction of liberty in various forms is justified with reference to health and safety of the individual and the community. The tension that arises from this has been construed as a hallmark of the practice and an ever-present quandary for practitioners. Stating this ethical dilemma upfront is a common point of departure for many texts discussing FMHS.
View Article and Find Full Text PDFCofactors facilitate bona fide prion misfolding in vitro but are not necessary for the infectivity of recombinant murine prions.
PLoS Pathog
January 2025
Center for Cooperative Research in Biosciences (CIC BioGUNE), Basque Research and Technology Alliance (BRTA), Derio, Spain.
Prion diseases, particularly sporadic cases, pose a challenge due to their complex nature and heterogeneity. The underlying mechanism of the spontaneous conversion from PrPC to PrPSc, the hallmark of prion diseases, remains elusive. To shed light on this process and the involvement of cofactors, we have developed an in vitro system that faithfully mimics spontaneous prion misfolding using minimal components.
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