Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.jhep.2021.04.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Non-HFE Hemochromatosis in the Context of β-Thalassemia Trait: A Case Study on Iron Overload Dysregulation.
Cureus
November 2024
Internal Medicine, Creighton University School of Medicine, St. Joseph's Hospital and Medical Center, Phoenix, USA.
Thalassemia and hemochromatosis are two distinct conditions that involve dysregulation of iron metabolism, though their origin, clinical presentations, and treatments differ. This case represents a patient with incidentally discovered microcytic anemia due to β-thalassemia trait and non- hemochromatosis. It discusses the potential synergistic effect of these two diseases on iron overload and highlights the need for further testing to determine hereditary versus secondary causes of hemochromatosis.
View Article and Find Full Text PDFA decade of iron overload disorders and hemochromatosis: clinical and genetic findings from a specialized center in Colombia.
Front Med (Lausanne)
December 2024
One Health Research Group, Univerisdad de las Americas, Quito, Ecuador.
Background: Iron overload disorders, including hereditary hemochromatosis (HH), are characterized by excessive iron accumulation, which can cause severe organ damage. HH is most associated with the C282Y mutation in Caucasian populations, but its prevalence and genetic profiles in Latin American populations remain underexplored.
Objectives: To describe the clinical manifestations, genetic profiles, and biochemical characteristics of patients with suspected iron overload disorders in a specialized hematology center in Cali, Colombia.
Direct Assessment of Hereditary Hemochromatosis in Preimplantation Genetic Testing.
F S Sci
December 2024
Orchid Health Genomic Lab, Durham, NC, 27703. Electronic address:
Objective: Hereditary hemochromatosis (HH) is a common genetic disorder characterized by iron overload, which, if undiagnosed, can lead to severe organ damage. There are four types of HH. Type 1 HH, the most common form, is primarily caused by a common variant in Western Europe (p.
View Article and Find Full Text PDFRejection in the setting of combined Heart and Liver Transplantation.
Int J Cardiol Congenit Heart Dis
March 2024
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Introduction: Each year the number of combined heart-liver transplants (HLT) increases, with two distinct patient populations proceeding down this pathway. The first are patients with congenital heart disease (CHD), most commonly single ventricle patients palliated with Fontan. The second group are those with long standing congestive hepatopathy, amyloidosis, hemochromatosis, or alcohol induced myopathies and liver disease.
View Article and Find Full Text PDFMildly Elevated Liver Transaminase Levels: Causes and Evaluation.
Am Fam Physician
December 2024
St. Luke's Family Medicine Residency-Sacred Heart Campus, Allentown, Penn.
Approximately 10% to 20% of the general population has elevated liver chemistry levels, including aspartate and alanine transaminases. Elevated transaminase levels may be associated with significant underlying liver disease and increased risk of liver-related and all-cause mortality. The most common causes of mildly elevated transaminase levels (two to five times the upper limit of normal) are metabolic dysfunction-associated steatotic liver disease (MASLD) and alcoholic liver disease.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!