The current study aimed to compare time spent above 90% V̇2max (tV̇2max) during 3 work-matched interval training protocols comprising 8×60-second exercise efforts with decreasing, increasing, or constant work rate distribution within each exercise interval. Ten healthy male subjects (age: 27.6±5.0 years; V̇2max: 3.82±0.52 L•min-1) performed an incremental test to determine V̇2max and peak power output (P max). During visits 2, 3, and 4, three work-matched interval training sessions comprising 8×60 s efforts: 60 s active recovery with the power output held constant (100%Pmax; ITCON), decreasing (from 110 to 90%Pmax; ITDEC), or increasing (from 90 to 110%Pmax; ITINC) linearly throughout each work interval. Time sustained above 90% of V̇2max (tV̇2max) or HRmax (tHRmax), blood lactate concentrations (BLC) and rating of perceived exertion (RPE) were measured. The tV̇2max (ITCON: 274±132; ITDEC: 313±102; ITINC: 310±113 s, P=0.37), tHRmax (ITCON: 396±180; ITDEC: 441±207; ITINC: 390±212 s, P=0.47), BLC (P=0.73), and final RPE (P=0.75) were similar among protocols. In conclusion, work-matched interval training induced similar time near V̇2max and associated physiological responses regardless of work rate manipulation.
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http://dx.doi.org/10.1055/a-1550-9977 | DOI Listing |
J Eval Clin Pract
February 2025
Department of Biostatistics and Medical Informatics, İnönü University Faculty of Medicine, Malatya, Turkey.
Rationale: Identifying whether perceived stigma or personal stigma more significantly affects nurses' attitudes towards seeking psychological help is essential for effectively addressing current challenges and facilitating early intervention for the well-being of nurses and their patients.
Aims And Objectives: The aim of this study was to explore the mediating roles of personal stigma and depression in the relationship between perceived stigma among nurses and their attitudes towards seeking psychological help.
Methods: The sample of this descriptive cross-sectional study consisted of 302 nurses working in a university hospital in southern Turkey, selected using the purposive sampling method, between April 1 and May 1, 2021.
EClinicalMedicine
October 2024
Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Center, St. Michael's Hospital, Unity Health Toronto, Toronto, ON M5B 1W8, Canada.
Background: Use of health applications (apps) to support healthy lifestyles has intensified. Different app features may support effectiveness, including gamification defined as the use of game elements in a non-game situation. Whether health apps with gamification can impact behaviour change and cardiometabolic risk factors remains unknown.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Medical Ultrasound, Jinshan Hospital of Fudan University, Shanghai, China.
Purpose: Acute fatty liver of pregnancy (AFLP) is a severe complication that can occur in the third trimester or immediately postpartum, characterized by rapid hepatic failure. This study aims to explore the changes in portal vein blood flow velocity and liver function during pregnancy, which may assist in the early diagnosis and management of AFLP.
Methods: This longitudinal study was conducted at a tertiary healthcare center with participants recruited from routine antenatal check-ups.
EClinicalMedicine
December 2024
Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Infant alertness and neurologic changes can reflect life-threatening pathology but are assessed by physical exam, which can be intermittent and subjective. Reliable, continuous methods are needed. We hypothesized that our computer vision method to track movement, pose artificial intelligence (AI), could predict neurologic changes in the neonatal intensive care unit (NICU).
View Article and Find Full Text PDFEClinicalMedicine
December 2024
Department of Pathology and Genetics, Laboratory of Cancer Medical Science, Hokuto Hospital, Obihiro, Hokkaido, Japan.
Background: Pancreatic cancer is highly aggressive and has a low survival rate primarily due to late-stage diagnosis and the lack of effective early detection methods. We introduce here a novel, noninvasive urinary extracellular vesicle miRNA-based assay for the detection of pancreatic cancer from early to late stages.
Methods: From September 2019 to July 2023, Urine samples were collected from patients with pancreatic cancer (n = 153) from five distinct sites (Hokuto Hospital, Kawasaki Medical School Hospital, National Cancer Center Hospital, Kagoshima University Hospital, and Kumagaya General Hospital) and non-cancer participants (n = 309) from two separate sites (Hokuto Hospital and Omiya City Clinic).
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