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Dr. Jekyll or Mr. Hyde: The multifaceted roles of miR-145-5p in human health and disease.
Noncoding RNA Res
April 2025
Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, Miami, FL 33199, USA.
MicroRNAs (miRNAs) are classified as small, non-coding RNAs that play crucial roles in diverse biological processes, including cellular development, differentiation, growth, and metabolism. MiRNAs regulate gene expression by recognizing complementary sequences within messenger RNA (mRNA) molecules. Recent studies have revealed that miR-145-5p functions as a tumor suppressor in several cancers, including lung, liver, and breast cancers.
View Article and Find Full Text PDFReduction and amalgamation of mercury in silver nanoparticle suspensions under dark conditions.
Chemosphere
December 2024
Department of Chemistry and Biochemistry, Florida International University, Miami, 11200 SW 8th St, Miami, FL 33199, United States; Institute of Environment, Florida International University, 11200 SW 8th St, Miami, FL33199, United States. Electronic address:
Mercury (Hg) is a global pollutant of concern, and its transport and transformation are controlled by various environmental factors, with aquatic particles being an important driver. Understanding the interactions between silver nanoparticles (AgNPs) and Hg under dark condition is a prerequisite for studying the extent of AgNPs interaction with light and its participation in Hg biogeochemical cycling. Herein, under laboratory experimental setting, it was found that the reduction of divalent Hg (Hg(II)) to gaseous elemental Hg (Hg) by AgNPs readily occurred.
View Article and Find Full Text PDFEsculin-loaded nanoparticles ameliorate adjuvant-induced polyarthritis via subduing inflammatory and oxidative stress biomarkers in Wistar rats.
Inflammopharmacology
December 2024
Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore Campus, Lahore, 5400, Pakistan.
Rheumatoid arthritis is an autoimmune disorder affecting multiple joints and requires lifelong treatment. Present study was designed to formulate Esculin-loaded chitosan nanoparticles (ENPs) and evaluation of its anti-inflammatory and anti-arthritic action. The acute toxicity study of ENPs was also performed.
View Article and Find Full Text PDFThe acute effect of E-cigarette use on pulmonary function: a nonrandomized controlled trial.
Eur Respir J
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Department of Epidemiology, Robert Stempel College of Public Health, Florida International University, 11200 SW 8th St, Miami, FL 33199, USA
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