The palladium-catalysed tandem aza-Heck-Suzuki and aza-Heck-carbonylation reactions of -phenyl hydroxamic ethers are reported. These formal alkene carboamination reactions provide highly versatile access to wide range complex, stereogenic secondary lactams and exhibit outstanding functional group tolerance and high diastereoselectivity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8246078 | PMC |
| http://dx.doi.org/10.1039/d1sc02075g | DOI Listing |
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