AI Article Synopsis
- Cardiogenic unilateral pulmonary edema (UPE) is a rare condition, making up only 2% of cardiogenic pulmonary edema cases, and is usually linked to severe mitral regurgitation, with this case being unique due to severe aortic regurgitation.
- The patient, diagnosed with infective endocarditis, exhibited symptoms of shortness of breath and was found to have UPE on initial imaging, leading to the diagnosis of severe acute aortic regurgitation through echocardiogram.
- This case emphasizes the need for prompt evaluation of heart valve issues to decrease high mortality risks associated with UPE, illustrating that early diagnosis is crucial in such rare conditions.
Article Abstract
Cardiogenic unilateral pulmonary edema (UPE) is an uncommon clinical entity and it represents just 2% of cardiogenic pulmonary edema with inclination for the right upper lobe and it is most commonly associated with severe mitral regurgitation. In our review, the literature does not include any UPE cases that are associated with severe aortic regurgitation (AR). Herein, we present a case with UPE, that includes a patient diagnosed with infective endocarditis who presented with shortness of breath. Initial chest imaging revealed UPE. Severe acute AR was diagnosed clinically and confirmed by echocardiogram, caused by vegetations on the non-coronary cusp of the aortic valve. The patient was transferred for emergent surgical intervention. This case underscores the importance of emergently evaluating valvular pathology to reduce the mortality rate that is associated with this condition. < In this study, we are highlighting the importance of having a high suspicion index to consider the diagnosis of unilateral pulmonary edema, as this condition is rare and hard to diagnose and carries a high mortality as well.>.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8258264 | PMC |
| http://dx.doi.org/10.1016/j.jccase.2020.12.009 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Association of Subcapsular Liver Hematoma With Preeclampsia, Eclampsia, or Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome.
Obstet Gynecol
January 2025
Division of Maternal-Fetal Medicine, Department of Obstetrics Gynecology and Reproductive Sciences, University of Texas Health Science Center at Houston, Houston, Texas.
Objective: To describe the presentation, outcomes, and management strategies for cases of subcapsular liver hematoma associated with preeclampsia, eclampsia, or HELLP (hemolysis, elevated liver enzymes, and low platelet count) syndrome.
Methods: This was a case series of individuals with subcapsular liver hematoma managed at a single level IV center over a 10-year period, from 2013 to 2024. Presenting signs and symptoms, laboratory findings, time of onset, management strategies, acute perinatal and maternal outcomes, and long-term outcomes such as subsequent pregnancies were reviewed in the medical record and recorded.
Efficacy and Renal Safety of Protocol-based 11.7% Hypertonic Saline Infusion Compared with 20% Mannitol in Patients with Elevated Intracranial Pressure: A Study Protocol for a Randomized Clinical Trial.
Electrolyte Blood Press
December 2024
Department of Internal Medicine, College of Medicine, Dankook University, Republic of Korea.
Background: Elevated intracranial pressure (ICP) is a potentially life-threatening condition requiring prompt intervention. While both mannitol and hypertonic saline (HTS) are commonly used hyperosmotic agents for treating elevated ICP, there is insufficient evidence comparing their renal safety profiles and overall effectiveness. This study protocol outlines a pragmatic randomized trial to compare protocol-based 11.
View Article and Find Full Text PDFEarly Results of an Infant Model of Orthotopic Cardiac Xenotransplantation.
J Heart Lung Transplant
January 2025
Division of Cardiac Surgery, Department of Surgery, Children's Hospital Los Angeles, Los Angeles, CA. Electronic address:
Objective: Genetically engineered porcine hearts may have an application for infants in need of a bridge to cardiac allotransplantation. The current animal model that resulted in 2 human applications has been validated in adult non-human primates only. We sought to create an infant animal model of life sustaining cardiac xenotransplantation to understand limitations specific to this age group.
View Article and Find Full Text PDFThe effect of tocilizumab treatment for skin fibrosis by inhibiting CD38 macrophages in systemic sclerosis.
Cell Immunol
December 2024
Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing 210023, China; Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing 210008, China. Electronic address:
Background: Dermal and pulmonary fibrosis are the main clinical symptoms of systemic scleroderma (SSc), for which there are no effective therapeutic agents. Tocilizumab is thought to improve the symptoms of fibrosis, but the effect of tocilizumab on dermal fibrosis has not been explored. This study aims to investigate the therapeutic effect of tocilizumab on skin fibrosis by inhibiting CD38 macrophages in the bleomycin-induced SSc mice model.
View Article and Find Full Text PDFAerosol inhalation of rhIL-10 improves acute lung injury in mice by affecting pulmonary neutrophil phenotypes through neutrophil-platelet aggregates.
Int Immunopharmacol
January 2025
School of Basic Medicine, Qingdao University, Qingdao, China. Electronic address:
This study investigates the therapeutic effects of recombinant human IL-10 (rhIL-10) administered via aerosol inhalation in acute lung injury (ALI), with a particular focus on neutrophils. It explores how rhIL-10, in the presence of platelets, modulates neutrophil polarization to ameliorate acute lung injury. Initially, the ALI model established in mice demonstrated that aerosol inhalation of rhIL-10 significantly mitigated the cytokine storm in the lungs, reduced pulmonary edema, and alleviated histopathological damage to lung tissue.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!