AI Article Synopsis
- A 47-year-old man with chronic fungal lung infection and recurrent pneumonia experienced worsening symptoms and was found to have angioinvasion from a lung lesion into a major artery.
- He underwent a successful left lung removal due to the risk of severe bleeding and the seriousness of his condition.
- The case highlights the importance of surgical options for patients with severe lung infections, as both invasive aspergillosis and pseudomonas infections are linked to high mortality rates.
Article Abstract
A 47-year-old Caucasian man on long-standing antifungal therapy for chronic necrotising aspergillosis and a history of recurrent pseudomonas pneumonias presented to the outpatient pulmonary clinic with dyspnoea and chest discomfort for 3 days. A CT angiography of the chest demonstrated angioinvasion from the previously noted left upper lobe cavitary lesion into the left main pulmonary artery, along with new consolidating lesions. Due to the high risk for massive haemoptysis, he was evaluated by thoracic surgery and underwent a successful left pneumonectomy. As invasive pulmonary aspergillosis is associated with high mortality, surgical intervention should always be considered, especially in those who develop extensive disease, despite being on aggressive antifungal therapy. Though minimally described in literature, invasive pulmonary pseudomonas also carries a high mortality risk. In our patient, cultures from the resected lung only demonstrated .
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8278921 | PMC |
| http://dx.doi.org/10.1136/bcr-2020-236887 | DOI Listing |
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