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Cannabinoids for Acute Postoperative Pain Management: A Systematic Review and Meta-Analysis of Clinical Trials.
Eur J Pain
March 2025
Universidad del Bosque, Bogotá, Colombia.
Background: Poor acute postoperative pain control, coupled with the use of intravenous medications with a limited and unsafety efficacy spectrum, has led to new therapeutic alternative explorations to reduce adverse events while increasing its analgesic efficacy. There cannabinoids have been proposed as a useful control agent in post-surgical pain. Nevertheless, to date, there is no solid evidence to evaluate them.
View Article and Find Full Text PDFUse of cannabinoids for acute postoperative pain.
Rev Esp Anestesiol Reanim (Engl Ed)
October 2024
Facultativo Anestesiología, Reanimación y Tratamiento del Dolor, Hospital de Manises, Manises, Spain.
Doubts about the efficacy of medicinal cannabis in the treatment of acute postoperative pain are well justified, at least in light of the information gathered from Google Scholar, Clinical Trials, PubMed, and Cochrane databases.The conflation of cannabis and cannabinoids engenders not only normative but also medical implications. Despite cannabinoids having evinced their efficacy in the treatment of various pathologies, they have yet to demonstrate such in the context of acute postoperative pain.
View Article and Find Full Text PDFCannabinoids as a Potential Alternative to Opioids in the Management of Various Pain Subtypes: Benefits, Limitations, and Risks.
Pain Ther
April 2023
University of Pittsburgh Medical Center, Susquehanna, Williamsport, PA, USA.
Article Synopsis
- Pain is a complex issue with various types, and while opioids have traditionally been used for treatment, their risks of addiction and fatalities have sparked interest in cannabinoids as an alternative.
- A study conducted in June 2022 reviewed the effectiveness of cannabinoids for managing different pain types, highlighting their potential as an adjunct or replacement for opioids, while focusing on recent and relevant research.
- The findings are mixed: cannabinoids have shown promise in treating chronic pain like neuropathic and geriatric pain, but evidence for their effectiveness in acute postoperative and most musculoskeletal pain is less clear, and there’s insufficient data comparing them directly to opioids.
Cannabinoids and acute/postoperative pain management.
Pain
August 2021
Department of Anesthesiology and Pain Medicine, Faculty of Medicine, Université de Montréal, Montreal, QC, Canada.
Analgesic efficacy of cannabinoids for acute pain management after surgery: a systematic review and meta-analysis.
Reg Anesth Pain Med
July 2020
Anesthesiology and Pain Medicine, Women's College Hospital, Toronto, Ontario, Canada.
Background: Evidence regarding the role of cannabinoids in managing acute postoperative pain is conflicting. The purpose of this systematic review and meta-analysis was to determine the analgesic efficacy of perioperative cannabinoid compounds for acute pain management after surgery.
Methods: Original research articles evaluating the addition of cannabinoids to standard opioid-based systemic analgesia (Control) in the postoperative period were sought.
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