Alginates are linear polymers comprising 40% of the dry weight of algae possess various applications in food and biomedical industries. Alginate oligosaccharides (AOS), a degradation product of alginate, is now gaining much attention for their beneficial role in food, pharmaceutical and agricultural industries. Hence this review was aimed to compile the information on alginate and AOS (prepared from seaweeds) during 1994-2020. As per our knowledge, this is the first review on the potential use of alginate oligosaccharides in different fields. The alginate derivatives are grouped according to their applications. They are involved in the isolation process and show antimicrobial, antioxidant, anti-inflammatory, antihypertension, anticancer, and immunostimulatory properties. AOS also have significant applications in prebiotics, nutritional supplements, plant growth development and others products.
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http://dx.doi.org/10.1080/10408398.2021.1946008 | DOI Listing |
Int J Biol Macromol
January 2025
Department of Clinical Laboratory, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, Shaanxi Province, China. Electronic address:
Alginate oligosaccharides (AOS) have gained attention for their capacity to regulate human health as prebiotics. Osteosarcopenia is a progressive disease of the musculoskeletal system and result in heavy burden of patients. Studies suggest that gut microbiota is involved in the pathogenesis of osteosarcopenia, whether AOS can improve the symptoms of osteosarcopenia by modulating gut microbiota remains to be elucidated.
View Article and Find Full Text PDFFood Res Int
January 2025
Center for Research and Development in Food Cryotechnology (CIDCA, CCT-CONICET), La Plata 1900, Argentina. Electronic address:
Layer-by-Layer (LbL) self-assembly encapsulation is a promising technology for the protection and delivery of lactic acid bacteria. However, laboratory-scale encapsulation is often time-consuming, involves intensive protocols tailored for small-scale operations, requires substantial amounts of energy and water, and results in a low yield of encapsulated biomass. Scaling-up this process to a bench-bioreactor scale is not simply a matter of increasing culture volume as different key parameters (not particularly relevant at lab scale) become critical, including biomass production, the number of polymer layers, and the biomass-to-polymer mass ratio.
View Article and Find Full Text PDFFront Microbiol
December 2024
Key Laboratory of Agro-Products Processing Technology of Shandong Province, Key Laboratory of Novel Food Resources Processing Ministry of Agriculture, Institute of Food & Nutrition Science and Technology, Shandong Academy of Agricultural Sciences, Jinan, China.
Alginate lyases can fully degrade alginate into various size-defined unsaturated oligosaccharide products by -elimination. Here, we identified the bifunctional endolytic alginate lyase Aly35 from the marine bacterium sp. Strain H204.
View Article and Find Full Text PDFMar Drugs
December 2024
Yantai Key Laboratory of Characteristic Agricultural Bioresource Conservation & Germplasm Innovative Utilization, School of Life Sciences, Yantai University, Yantai 264000, China.
Marine bacteria are crucial sources of alginate lyases, which play an essential role in alginate oligosaccharide (AOS) production. This study reports the biochemical characteristics of a new species of the genus, sp. HZ11.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Shanghai Frontier Science Center of Optogenetic Techniques for Cell Metabolism, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China.
Inflammatory bowel disease involves excess reactive oxygen species (ROS) and hydrogen sulfide (HS) at inflammatory sites. Nanozyme-mediated ROS and HS scavenging therapy is promising for colitis treatment. Here, we synthesized a multiple ROS scavenging CuO nanoparticle and first explored its HS scavenging capacity.
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