Flavonoid glycosides from the fruits of and their anti-oxidant and -glucosidase inhibitory activities.

J Asian Nat Prod Res

School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China.

Published: August 2021

Three new flavonoid glycosides, embeliaflavosides A-C (), together with eight known flavonoid glycosides (), were isolated from the fruits of . Their structures were established based on the analyses of spectroscopic data. Compounds were evaluated for antioxidant and -glucosidase inhibitory activities. The results revealed that compounds owned significant ABTS radical scavenging activity with IC values of 2.52-9.78 µM, and DPPH scavenging activity with IC values of 7.56-26.47 µM, respectively. However, -glucosidase inhibition assay indicated that all the isolates were inactive.[Formula: see text].

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Source
http://dx.doi.org/10.1080/10286020.2020.1776266DOI Listing

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