A total of 101 patients suffering from slowly progressive schizophrenia with hypochondriac symptomatology and a manifestation or a relapse of the disease in the involutional age have been studied. Three variants of the disease course have been identified. The authors have considered the significance of sex, premorbid peculiarities of the personality, aggravated heredity, as well as the rate and character of exogenic manifestations in the patient's history as possible pathogenetic factors of a late manifestation (recurrence) of the disease. The incidence of adynamic-anergic component of depression in the involutional period is correlated with processes of accelerated mental ageing in schizophrenic patients with exogenously aggravated history. Cases with the first manifest attack in the involutional period have been referred to true late schizophrenia.
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