We present 10 patients with infection in whom next-generation sequencing of microbial cell-free deoxyribonucleic acid (mcfDNA) was used as a diagnostic tool. mcfDNA was detected in all cases and was more rapid and specific than rickettsial serology. mcfDNA impacted antibiotic management in 50% of patients.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266567PMC
http://dx.doi.org/10.1093/ofid/ofab147DOI Listing

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