AI Article Synopsis

  • A 72-year-old Chinese patient with exudative age-related macular degeneration experienced severe vision loss in the left eye and showed signs of latent ocular tuberculosis.
  • Retrospective imaging analysis revealed severe choroidal neovascularization and choroiditis, along with positive tuberculosis tests, indicating a complex diagnosis.
  • The case illustrates the difficulties in diagnosing intraocular tuberculosis due to its variable symptoms and limited access to biopsies, potentially leading to misdiagnosis and delayed treatment.

Article Abstract

An otherwise healthy 72-year-old Chinese patient diagnosed with exudative age-related macular degeneration and decreased vision in left eye was fully investigated. The retrospective analysis of past multimodal imaging revealed bilateral severe choroidal neovascularization and choroiditis associated with a positive tuberculin skin testing and interferon-gamma release assay (QuantiFERON-TB Gold - Cellestis, Chadstone, VIC, Australia) suggestive of latent ocular tuberculosis. The variable presentation and tests' results interpretation represent the greatest limitations in understanding and treating intraocular TB (IOTB). This may present without any other systemic symptoms, the intraocular tissues are of limited access to biopsies and other tests, including imaging and immunological tests, are of relative value. This case highlights how variable may be the presentation of IOTB, which can be easily misdiagnosed leading to a delayed treatment and worse prognosis.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255741PMC
http://dx.doi.org/10.1159/000512578DOI Listing

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