The supplemental feeding of wildlife is a worldwide phenomenon. The most widespread and socially accepted example is bird feeding. Commercial hedgehog (Erinaceus europaeus L.) diets are readily available in Switzerland. To test the hypothesis that commercial hedgehog diets are nutritionally inadequate, the following parameters (as taken from the label) of five commercial diets (three dry and two wet) were compared to the natural diet of E. europaeus: List of feed materials, crude ash (CA), crude protein (CP), crude fibre (CF), ether extract (EE) and nitrogen-free extracts (NfE). To test the second hypothesis, that feed labels of commercially available hedgehog diets in Switzerland are in accordance with Swiss and European law, the following parameters were assessed: Type of feed, net quantity, moisture content, instructions for proper use, list of the feed materials and claims. In all dry diets, the first ingredient was cereals (38.8%-50%), whereas in both wet diets, it was meat and meat by-products (51% in one product). Only one product had a CP content comparable to that of the natural diet and four products had a higher NfE content. Overall, the wet products were more comparable to the natural diet, especially regarding CP and NfE content. Of the five examined diets, three were labelled as complete feeds and two as compound feeds. The label analysis revealed inaccuracies and possible misleading information on two products. In conclusion, the use of commercial dry hedgehog diets should be discouraged as they do not resemble the natural diet of E. europaeus and are likely nutritionally inadequate. The commercial wet hedgehog diets should only be used supplementary. The feed labels of commercially available hedgehog diets were not always in compliance with Swiss and European law. The public should be educated about feeding E. europaeus and the risks of commercial diets for wildlife.
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http://dx.doi.org/10.1111/jpn.13561 | DOI Listing |
Carcinogenesis
January 2025
Instituto de Investigaciones en Ciencias de la Salud, INICSA (CONICET - FCM UNC), 5016 Córdoba, Argentina.
Pancreatic cancer is a devastating malignancy in great need of new and more effective treatment approaches. In recent years, studies have indicated that nutritional interventions, particularly nutraceuticals, may provide novel avenues to modulate cancer progression. Here, our study characterizes the impact of ω-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), as a nutraceutical intervention in pancreatic cancer using a genetically engineered mouse model driven by KrasG12D and Trp53R172H.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Laboratory of Analysis of Gastrointestinal Tract Protective Barrier, Department of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Instytucka 3, 05-110 Jabłonna, Poland.
The hedgehog (Hh) signalling pathway plays a key role in both embryonic and postnatal development of the intestine and is responsible for gut homeostasis. It regulates stem cell renewal, formation of the villous-crypt axis, differentiation of goblet and Paneth cells, the cell cycle, apoptosis, development of gut innervation, and lipid metabolism. Ligands of the Hh pathway, i.
View Article and Find Full Text PDFJ Nutr Biochem
February 2025
Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, Guangdong Second Provincial General Hospital, Guangzhou, China. Electronic address:
Maternal low protein diet around pregnancy reduces the primordial follicles in offspring ovary. Resolving cellular and molecular mechanisms associated with low protein diet is therefore urgently needed for the guidance of dietary interventions. Here, we utilized single-cell and spatial RNA-seq to create transcriptomic atlases of offspring ovaries from maternal low protein diet mice.
View Article and Find Full Text PDFExp Mol Med
October 2024
Laboratory of Developmental Biology and Genomics, College of Veterinary Medicine, Interdisciplinary Program for Bioinformatics and Program for Cancer Biology, Seoul National University, Seoul, 08826, Republic of Korea.
PDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic stimuli. To elucidate the molecular heterogeneity of ASCs, we conducted single-cell transcriptomic profiling of PDGFRA+ cells isolated from the inguinal WAT (iWAT) of mice treated with the beta3 adrenergic receptor agonist CL316243. Single-cell RNA-seq revealed nine major clusters, which were categorized into four groups: resting, proliferating, differentiating, and adipogenic factor-expressing cells (AFECs).
View Article and Find Full Text PDFFront Pharmacol
September 2024
Department of Pharmacology and Therapeutics, College of Medicine, Qassim University, Buraidah, Saudi Arabia.
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