Evaluation of gingival microcirculation in patients with gestational diabetes mellitus.

Microvasc Res

Department of Internal Medicine, Faculty of Medicine, Sakarya University, Sakarya, Turkey.

Published: November 2021

AI Article Synopsis

  • The study aimed to investigate differences in microcirculation at the periodontal mucous level in pregnant women with gestational diabetes mellitus (GDM).
  • A total of 55 participants were analyzed, with 30 diagnosed with GDM and 25 healthy control participants, using advanced optical techniques to assess capillary characteristics in the gums.
  • Results showed that GDM patients had higher capillary density but lower tortuosity compared to healthy controls, suggesting unique microcirculatory changes in periodontal tissues related to GDM.

Article Abstract

Objective: The aim of this study was to evaluate the possible microcircularity variations at periodontal mucous level in patients with gestational diabetes mellitus (GDM).

Material And Methods: Overall 55 periodontally healthy and non-smoker participants were enrolled in the study by whom 30 were diagnosed with GDM (26 to 34 weeks pregnant) and 25 were systemically healthy unpregnant controls. The analysis was performed in the masticatory/gingival mucosa of maxillary anterior region and by the optical probe videocapillaroscopy technique equipped with 200× lenses. The following parameters were recorded: capillary loop visibility, capillary orientation to surface, microhemorrhages, capillary density and tortuosity.

Results: The average capillary density was significantly higher in participants with GDM (27 ± 5.46 no. loops/mm) compared to controls (21.16 ± 3 no. loops/mm) (P = 0.035) while increased tortuosity scores was observed in controls compared with the GDM group (P = 0.017). There was not any significantly difference between study groups among the other variables (P > 0.05).

Conclusions: Capillary alterations including capillary density and tortuosity were demonstrated in gingival microcirculation of patients with GDM. These microcirculatory changes could provide us new understanding on the dynamics of the relationship between GDM and periodontal tissues.

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Source
http://dx.doi.org/10.1016/j.mvr.2021.104222DOI Listing

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