to evaluate the effect of pseudoexfoliation syndrome (PXF) on the stage of age-related macular degeneration (AMD) and central retinal thickness, measured by optical coherence tomography (OCT) in elderly patients living in Saint-Petersburg. 25 elderly patients (30 eyes) with PXF and 25 age-matched patients (29 eyes) without PXF (control group) were included in the study. Retinal thickness in fovea and parafovea as well as AMD stage were compared in the groups. Thickness of fovea and parafovea was measured with OCT, the stage of AMD was graded according AREDS criteria. The mean fovea and parafovea thickness in PXS group were not significantly different compared with control group (p>0,05). There was no significant difference between two groups in the stage of AMD, graded according AREDS criteria (p>0,05). The effect of PXS on central retinal thickness and the stage of AMD was not found in Saint-Petersburg elderly population.

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