In TAE Technologies' current experimental fusion device, C-2W (also called "Norman"), record breaking, advanced beam-driven field-reversed configuration plasmas are produced and sustained in steady state utilizing variable-energy neutral beams, expander divertors, end-bias electrodes, and an active plasma control system. With a rapid shot-pace and an extensive number of data channels, the amount of data generated necessitates automated signal processing. To this end, a machine learning algorithm consisting of a multi-layered neural network as well as other data processing software has been designed for signal feature identification, allowing for accurate and fast signal classification, anomalous condition detection, and providing for signal pre-processing. With a small set of training data, the neural network can be "bootstrapped" to provide a robust classification system while minimizing human oversight. An example using data from the theta pinch plasma formation pulsed power system is presented. With an overall accuracy of ∼97%-having classified more than 5 × 10 pulsed power signals-the classification scheme is more than sufficient to fine-tune machine set points. However, this technique can be used for near-real-time preprocessing of any plasma physics signal and has wide ranging application in fusion experiments for the varied data produced by plasma diagnostics.
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http://dx.doi.org/10.1063/5.0043820 | DOI Listing |
SLAS Discov
January 2025
Center for Discovery and Innovation, Hackensack Meridian Health, 111 Ideation Way. Nutley, New Jersey 07110, United States. Electronic address:
The COVID-19 pandemic has emphasized the necessity for rapid and adaptable drug screening platforms against live pathogenic viruses that require high levels of biosafety containment. Conventional antiviral testing is time-consuming and labor-intensive. Here, we outline the design and validation of a semi-automated drug-screening platform for SARS-CoV-2 that utilizes multiple liquid handlers, a stable A549 cell line expressing ACE2 and TMPRSS2 receptors, and a recombinant SARS-CoV-2 strain harboring the nano-luciferase gene.
View Article and Find Full Text PDFMicron
January 2025
Department of Materials Science and Engineering, The Iby and Aladar Fleischman Faculty of Engineering, Tel Aviv University, Tel Aviv 6997801, Israel. Electronic address:
Atomic-scale metrology in scanning transmission electron microscopy (STEM) allows to measure distances between individual atomic columns in crystals and is therefore an important aspect of their structural characterization. Furthermore, it allows to locally resolve strain in crystals and to calibrate precisely the pixel size in STEM. We present a method dedicated to the evaluation of interplanar spacing (d-spacing) based on an algorithm including curve fitting of processed high-angle annular dark-field STEM (HAADF STEM) signals.
View Article and Find Full Text PDFPLoS One
January 2025
National Heart and Lung Institute, Imperial College London, London, United Kingdom.
Introduction: Haemodynamic atrioventricular delay (AVD) optimisation has primarily focussed on signals that are not easy to acquire from a pacing system itself, such as invasive left ventricular catheterisation or arterial blood pressure (ABP). In this study, standard clinical central venous pressure (CVP) signals are tested as a potential alternative.
Methods: Sixteen patients with a temporary pacemaker after cardiac surgery were studied.
J Acoust Soc Am
January 2025
Key Laboratory of Underwater Acoustic Communication and Marine Information Technology of the Ministry of Education, College of Ocean and Earth Sciences, Xiamen University, Xiamen 361005, China.
Odontocetes are capable of dynamically changing their echolocation clicks to efficiently detect targets, and learning their clicking strategy can facilitate the design of man-made detecting signals. In this study, we developed deep convolutional generative adversarial networks guided by an acoustic feature vector (AF-DCGANs) to synthesize narrowband clicks of the finless porpoise (Neophocaena phocaenoides sunameri) and broadband clicks of the bottlenose dolphins (Tursiops truncatus). The average short-time objective intelligibility (STOI), spectral correlation coefficient (Spe-CORR), waveform correlation coefficient (Wave-CORR), and dynamic time warping distance (DTW-Distance) of the synthetic clicks were 0.
View Article and Find Full Text PDFEur Heart J Cardiovasc Imaging
January 2025
Departments of Medicine (Division of Artificial Intelligence in Medicine), Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Aims: Proximal coronary artery calcium (CAC) may improve prediction of major adverse cardiac events (MACE) beyond the CAC score, particularly in patients with low CAC burden. We investigated whether the proximal CAC can be detected on gated cardiac computer tomography (CT) and whether it provides prognostic significance with artificial intelligence (AI).
Methods And Results: A total of 2016 asymptomatic adults with baseline CAC CT scans from a single site were followed up for MACE for 14 years.
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