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Distinguishing benign and malignant myxoid soft tissue tumors: Performance of radiomics vs. radiologists.
PLoS One
January 2025
Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.
Introduction: Benign and malignant myxoid soft tissue tumors have shared clinical, imaging, and histologic features that can make diagnosis challenging. The purpose of this study is comparison of the diagnostic performance of a radiomic based machine learning (ML) model to musculoskeletal radiologists.
Methods: Manual segmentation of 90 myxoid soft tissue tumors (45 myxomas and 45 myxofibrosarcomas) was performed on axial T1, and T2FS or STIR magnetic resonance imaging sequences.
We report on the design and fabrication of a novel circular pillar array as an interfacial barrier for microfluidic microphysiological systems ( ). Traditional barrier interfaces, such as porous membranes and microchannel arrays, present limitations due to inconsistent pore size, complex fabrication and device assembly, and lack of tunability using a scalable design. Our pillar array overcomes these limitations by providing precise control over pore size, porosity, and hydraulic resistance through simple modifications of pillar dimensions.
View Article and Find Full Text PDFTransformative social innovation and rural collaborative workspaces: assembling community economies in Austria and Greece.
Open Res Eur
January 2025
Department of Economic and Regional Development,, Panteion University of Social and Political Sciences, Athens, L. Syggrou 136, 16761, Greece.
Background: Collaborative Workspaces are rapidly growing and evolving across the world. Traditionally understood as an urban phenomenon, most research understands them as either 'entrepreneurial-led', as profit-driven and commercial spaces such as business incubators and accelerators, or 'community-led' as being bottom-up, not-for-profit ventures aimed at catering for the needs of their community. Recent years however have seen their diffusion beyond large urban agglomerations to small towns and villages, with their functions assumed to be more community-orientated.
View Article and Find Full Text PDFRelation between dimensional distinctiveness and comparison format in a novel noun generalization task in preschoolers.
Front Psychol
January 2025
LEAD, CNRS, UMR 5022, Université Bourgogne Europe, Dijon, France.
Numerous studies have shown that in novel noun generalization tasks, the simultaneous presentation of multiple learning examples increases the percentage of generalizations that are based on less salient properties, compared to the presentation of a single learning example. In this research with preschoolers ( = 300) we demonstrate that this effect can be modulated by dimensional distinctiveness, i.e.
View Article and Find Full Text PDFPreparation and application of a multiepitope fusion protein based on bioinformatics and Tandem Mass Tag-based proteomics technology.
Front Immunol
January 2025
Jiangsu Engineering Research Center of Biological Data Mining and Healthcare Transformation, Xuzhou Medical University, Xuzhou, China.
Introduction: Brucellosis is a widespread zoonotic disease that poses a considerable challenge to global public health. Existing diagnostic methods for this condition, such as serological assays and bacterial culture, encounter difficulties due to their limited specificity and high operational complexity. Therefore, there is an urgent need for the development of enhanced diagnostic approaches for brucellosis.
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