AI Article Synopsis
- The study systematically reviews the international literature on dynamic sleep MRI as a diagnostic tool for obstructive sleep apnea (OSA) and includes a meta-analysis of quantitative data.
- Nineteen articles involving 410 OSA patients and 79 controls were analyzed, revealing high rates of retropalatal (98%) and retroglossal (41%) obstructions, with sedation greatly improving patient sleep rates during MRI.
- The findings highlight the prevalence of specific types of airway obstruction in OSA and suggest a need for standardization in dynamic sleep MRI methodology for future research and clinical use.
Article Abstract
Purpose: The objective of this study is to systematically review the international literature for dynamic sleep magnetic resonance imaging (MRI) as a diagnostic tool in obstructive sleep apnea (OSA), to perform meta-analysis on the quantitative data from the review, and to discuss its implications in future research and potential clinical applications.
Study Design: A comprehensive review of the literature was performed, followed by a detailed analysis of the relevant data that has been published on the topic.
Methods: Clinical key, Uptodate, Ovid, Ebscohost, Pubmed/MEDLINE, Scopus, Dynamed, Web of Science and The Cochrane Library were systematically searched. Once the search was completed, dynamic sleep MRI data were analyzed.
Results: Nineteen articles reported on 410 OSA patients and 79 controls that underwent dynamic sleep MRI and were included in this review. For meta-analysis of dynamic sleep MRI data, eight articles presented relevant data on 160 OSA patients. Obstruction was reported as follows: retropalatal (RP) 98%, retroglossal (RG) 41% and hypopharyngeal (HP) in 5%. Lateral pharyngeal wall (LPW) collapse was found in 35/73 (48%) patients. The combinations of RP + RG were observed in 24% and RP + RG + LPW in 16%. If sedation was used, 98% of study participants fell asleep compared to 66% of unsedated participants.
Conclusions: Dynamic sleep MRI has demonstrated that nearly all patients have retropalatal obstruction, retroglossal obstruction is common and hypopharyngeal obstruction is rare. Nearly all patients (98%) who are sedated are able to fall asleep during the MRI. There is significant heterogeneity in the literature and standardization is needed.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8266991 | PMC |
| http://dx.doi.org/10.1007/s00405-021-06942-y | DOI Listing |
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