Background: Performing a cardiac CT scan before ablation provides a better understanding of the anatomical variations of the left atrium and pulmonary veins, as well as an analysis of coronary anatomy and the calcium score. The aim of the present study was to determine whether the CT characteristics of patients with unknown CAD have an impact on recurrence of AF.
Methods: This monocentric retrospective study included patients with AF who had undergone cardiac CT prior to a single ablation.
Results: Among the 229 patients included in the study, 70 (30.5%) presented AF recurrence between 3 and 12 months after a single ablation. The prevalence of CAD confirmed by CT coronary angiogram and the coronary calcium score were similar in the two groups. Patients with recurrent atrial fibrillation had a significantly higher LAVI evaluated by CT scan than patients without recurrence. The ROC curve determined an optimal LAVI threshold of 49 mL/m. In multivariate analysis, the LAVI measured by CT scan was independently associated with the risk of AF recurrence.
Conclusions: Our study confirms that CAD is not a predictor of AF recurrence after a single ablation, unlike the LAVI. Further studies are necessary to re-evaluate the long-term conclusions of this work.
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http://dx.doi.org/10.1007/s10840-021-01018-7 | DOI Listing |
Anal Bioanal Chem
January 2025
Molecular Horizons and School of Chemistry and Molecular Bioscience, University of Wollongong, Wollongong, Australia.
The wide range of mass spectrometry imaging (MSI) technologies enables the spatial distributions of many analyte classes to be investigated. However, as each approach is best suited to certain analytes, combinations of different MSI techniques are increasingly being explored to obtain more chemical information from a sample. In many cases, performing a sequential analysis of the same tissue section is ideal to enable a direct correlation of multimodal data.
View Article and Find Full Text PDFJ Cardiol Cases
October 2024
Department of Cardiology, Mater Dei Hospital, Msida, Malta.
Unlabelled: Pulmonary vein (PV) stenosis is a rare complication following PV isolation (PVI) for atrial fibrillation. Despite the benefit of early intervention, screening is not conducted, emphasizing the importance of maintaining a high index of suspicion. Standardized management approaches are unavailable for this serious complication.
View Article and Find Full Text PDFHealth Inf Sci Syst
December 2025
Beijing Anngeen Technology Co., ltd, Beijing, 100176 Beijing China.
Early diagnosis and treatment of myocardial infarction (MI) can significantly reduce the severity of the disease. Disease data are often imbalanced, which can lead to poor prediction outcomes when using conventional models. Therefore, developing a risk prediction model for MI with imbalanced datasets has become challenging.
View Article and Find Full Text PDFJ Interv Card Electrophysiol
January 2025
Department of Cardiology, Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, 310009, Zhejiang, China.
Background: Slow activation areas, characterized by decreased conduction velocities in the left atrium, are commonly observed in patients with persistent atrial fibrillation (PeAF). However, it remains unclear whether the ablation of slow activation areas combined with pulmonary vein isolation (PVI) improves clinical outcomes in these patients.
Methods: This single-center retrospective study included patients who underwent catheter ablation for PeAF.
Bone Res
January 2025
Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong SAR, China.
Fibrotic remodeling of nucleus pulposus (NP) leads to structural and mechanical anomalies of intervertebral discs that prone to degeneration, leading to low back pain incidence and disability. Emergence of fibroblastic cells in disc degeneration has been reported, yet their nature and origin remain elusive. In this study, we performed an integrative analysis of multiple single-cell RNA sequencing datasets to interrogate the cellular heterogeneity and fibroblast-like entities in degenerative human NP specimens.
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